Some investigators have attempted to estimate the Reynolds shear stress on the basis of a single component of velocity. The purpose of this investigation is to determine the validity of such estimates in a complex flow field, such as occurs in the cardiovascular system in the region of the aortic valve. Turbulent velocities were obtained in an in vitro pulse duplicating system with a two-channel laser Doppler anemometer. Velocities were measured in the region of two stenotic natural aortic valves and a normal stent mounted porcine bioprosthetic valve. Constants of proportionality between the Reynolds shear stress, averaged over ejection, and the Reynolds normal stress were determined. The constants of proportionality depended upon the local conditions, namely, whether the valves were stenotic or normal bioprosthetic. There was wide scatter of data. This suggests that any estimate of the Reynolds shear stress, based upon a single axial velocity in a complex flow field, such as occurs in the cardiovascular system, is likely to be inaccurate.
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http://dx.doi.org/10.1007/BF02371247 | DOI Listing |
Electromagn Biol Med
January 2025
Department of Applied Mathematics, University of Calcutta, Kolkata, India.
The current investigation explores tri-hybrid mediated blood flow through a ciliary annular model, designed to emulate an endoscopic environment. The human circulatory system, driven by the metachronal ciliary waves, is examined in this study to understand how ternary nanoparticles influence wave-like flow dynamics in the presence of interfacial nanolayers. We also analyze the effect of an induced magnetic field on Ag-Cu-/blood flow within the annulus, focusing on thermal radiation, heat sources, buoyancy forces and ciliary motion.
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December 2024
Jiangsu Key Laboratory of Oil-Gas Storage and Transportation Technology, Changzhou University, Changzhou, 213164, Jiangsu, China.
Bend pipe is a common part of long distance pipeline. There is very important to study the flow law of hydrate particles in the bend pipe, and pipeline design will be optimized. In addition, the efficiency and safety of pipeline gas transmission will be improved.
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December 2024
College of Civil Engineering, Guizhou University, Huaxi District, Guiyang, 550025, Guizhou, China.
In order to investigate the influence of shear on contact characteristics and fluid flow evolution of rough rock fractures, a series of shear-flow tests were carried out by numerical experiments. Firstly, a sandstone specimen with a rough fracture was made in the laboratory, and the numerical model of the fracture was reconstructed in FLAC3D software. Experiments were conducted to investigate the depth of penetration of the fracture under different normal stress (1, 3, and 5 MPa) and shear displacement (2, 4, 6, 8, and 10 mm).
View Article and Find Full Text PDFmedRxiv
December 2024
Department of Psychiatry, New York University Grossman School of Medicine, New York, New York.
Unlabelled: Although evidence-based treatments for Prolonged Grief Disorder (PGD) exist, pretreatment characteristics associated with differential improvement trajectories have not been identified. To identify clinical factors relevant to optimizing PGD treatment outcomes, we used unsupervised and supervised machine learning to study treatment effects from a double-blinded, placebo-controlled, randomized clinical trial. Participants were randomized into four treatment groups for 20 weeks: citalopram with grief-informed clinical management, citalopram with prolonged grief disorder therapy (PGDT), pill placebo with PGDT, or pill placebo with clinical management.
View Article and Find Full Text PDFBiomater Adv
December 2024
Department of Biochemistry and Chemistry, School of Agriculture, Biomedicine and Environment, La Trobe University, Melbourne, Victoria 3086, Australia; The Biomedical and Environmental Sensor Technology (BEST) Research Centre, Biosensors Program, La Trobe Institute for Molecular Science (LIMS), La Trobe University, Melbourne, Victoria 3086, Australia. Electronic address:
There is a pressing need for new cell-laden, printable, biomaterials that are rigid and highly biocompatible. These materials can mimic stiffer tissues such as cartilage, fibrotic tissue and cancer microenvironments, and thus have exciting applications in regenerative medicine, wound healing and cancer research. Self-assembled peptides (SAPs) functionalised with aromatic groups such as Fluorenyl-9-methoxycarbonyl (Fmoc) show promise as components of these biomaterials.
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