Non-surgical procedures such as fillers, PRP and derivatives, energy-based devices and adipose derivate mesenchymal stem cell treatments are begun to be used in women genital area for both functional and aesthetic purposes. After theproduction of injectable HA for genital use, patients were able to benefit more effectively from these applications and its use in the vagina became more common. In our study, we aimed to demonstrate a new intravaginal injection technique, Cannulated Intravaginal Injection Technique (CIVIT) that we can perform vaginal injection more homogenously and less traumatic and more effectively to the entire vaginal mucosa. Retrospectively, the data of 44 patients who underwent intravaginal injection of HA manufactured for genital use at a private Female Health Clinic were analyzed. Of the 44 patients, 21 were injected using the random needling technique, and 22 were injected using CIVIT. All patients had symptoms of genitourinary syndrome (GUS), a vaginal health index below 15, and were compared based on the Female Sexual Function Index (FSFI) and visual analogue scale (VAS) for GUS before and after the procedures. It was observed that all post-injection values, except for FSFI arousal (p = 0.539), were statistically significantly higher in the CIVIT group (P = 0.001). Post injection dryness, dyspareunia and discomfort values decreased significantly in the CIVIT group compared to the Random Needling group. Our new technique, CIVIT, and random injection, which is a frequently used technique, are two effective techniques for vaginal rejuvenation. However, CIVIT is significantly more effective than the random technique in improving genitourinary symptoms, vaginal health index and sexual function.
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http://dx.doi.org/10.1038/s41598-025-91069-x | DOI Listing |
Anim Reprod Sci
March 2025
Embrapa Caprinos e Ovinos, Estrada Sobral/Groaíras, km 04, CP 145, Sobral, CE CEP 62010-970, Brazil.
The objective was to evaluate the effects of intramuscular (i.m.) human chorionic gonadotropin (hCG) administered on day 5 (D5) or day 7 (D7) after estrus (D0) on luteal structures (number, area, vascularization, and progesterone secretion) and pregnancy rates in estrus-induced dairy goats during the non-breeding season.
View Article and Find Full Text PDFBMC Pregnancy Childbirth
March 2025
Department of Anatomy, School of Medicine, Tehran University of Medical Sciences, Pour Sina St, Tehran, 1416753955, Iran.
Background: Infertility treatments are continually evolving, with vaginal probiotic supplementation before embryo transfer (ET) being explored as a potential method to improve clinical outcomes. So, this systematic review evaluated the effect of vaginal probiotics on pregnancy rates following ET.
Methods: Studies were identified through PubMed, Scopus, Web of Science, Cochrane, and clinical trial registries up to October 17, 2024.
Gates Open Res
March 2025
Médecins Sans Frontières, Harare, Zimbabwe.
Background: Expanding contraceptive options could better meet users' diverse needs and preferences. Annovera is a contraceptive vaginal ring that provides a year of pregnancy prevention while remaining under user control and allowing for regular menstrual cycles. This method may also help to reduce burdens on some health care and supply chain systems.
View Article and Find Full Text PDFNon-surgical procedures such as fillers, PRP and derivatives, energy-based devices and adipose derivate mesenchymal stem cell treatments are begun to be used in women genital area for both functional and aesthetic purposes. After theproduction of injectable HA for genital use, patients were able to benefit more effectively from these applications and its use in the vagina became more common. In our study, we aimed to demonstrate a new intravaginal injection technique, Cannulated Intravaginal Injection Technique (CIVIT) that we can perform vaginal injection more homogenously and less traumatic and more effectively to the entire vaginal mucosa.
View Article and Find Full Text PDFBMC Vet Res
March 2025
Department of Physiology, Veterinary Faculty, Complutense University of Madrid, 28040, Madrid, Spain.
Background: Rabbits are an induced-ovulatory species such that exogenous hormone factors are needed to induce ovulation. Traditionally, intramuscular injections of gonadotropin-releasing hormone (GnRH) analogues are given at the time of artificial insemination (AI). To avoid the need for injections, the intravaginal delivery of molecules naturally present in seminal plasma has been explored.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!