Purpose: Faith-based organizations (FBOs) have been recognized as a critical partner to reach underserved, marginalized populations in the U.S. for disease prevention and health promotion. FBOs have been successfully engaged to lower risk for leading causes of death, including cancer, but despite the proliferation of FBO cancer intervention research, a comprehensive review is lacking.
Methods: We conducted a PRISMA Scoping Review to ascertain the impact of FBO cancer interventions. Seven bibliographical databases were used to search for articles evaluating cancer interventions reporting quantitative outcomes in which places of worship in the U.S. served as the research location. Study characteristics and results data were extracted by two independent extractors.
Results: Thirty-six studies were included. All FBOs were Christian churches with healthy populations. Breast (25%), prostate (22%), and colorectal (17%) were the primary cancers targeted and cancer screening was the primary outcome of 75% of studies. Sixty-nine percent (k = 25) reported significant results in cancer-related outcomes from baseline to post-intervention follow-up, with 100% of studies in Korean American communities (k = 7) reporting significant results.
Conclusion: FBO interventions can successfully increase preventative screening across numerous cancer types in diverse communities, particularly in Korean Americans. Additional FBO cancer interventions that aim to reduce inequities in other cancers (e.g., lung) that disproportionately affect Korean Americans and have not been targeted are warranted. Expanding current investigations of FBO collaborations with other faiths (besides Christian) to include cancer prevention and control would further realize FBOs' untapped potential.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/s10552-025-01977-6 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Long term latency of highly mutated cells in normal mouse skin is reversed by exposure to tumor promoters and chronic tissue damage.
Cancer Discov
March 2025
University of California, San Francisco, San Francisco, CA, United States.
Historical studies performed nearly a century ago using mouse skin models identified two key steps in cancer evolution: initiation, a likely mutational event, and promotion, driven by inflammation and cell proliferation. Initiation was proposed to be permanent, with promotion as the critical rate-limiting step for cancer development. Here, we carried out whole genome sequencing to demonstrate that initiated cells with thousands of mutagen-induced mutations can persist for long periods and are not removed by cell competition or by immune intervention, thus mimicking the persistence of cells with cancer driver mutations in normal human tissues.
View Article and Find Full Text PDFIt is known that inhibition of the endoplasmic reticulum transmembrane signaling protein (ERN1) suppresses the glioblastoma cells proliferation. The present study aims to investigate the impact of inhibition of ERN1 endoribonuclease and protein kinase activities on the , , and gene expression in U87MG glioblastoma cells with an intent to reveal the role of ERN1 signaling in the regulation of expression of these genes. The U87MG glioblastoma cells with inhibited ERN1 endoribonuclease (dnrERN1) or both enzymatic activities of ERN1 (endoribonuclease and protein kinase; dnERN1) were used.
View Article and Find Full Text PDFThe ERN1 signaling pathway of unfolded protein controls the expression of EDEM1 and its hypoxic regulation in glioblastoma cells.
Endocr Regul
January 2025
1Department of Molecular Biology, Palladin Institute of Biochemistry, National Academy of Sciences of Ukraine, Kyiv, Ukraine.
For the effective growth of malignant tumors, including glioblastoma, the necessary factors involve endoplasmic reticulum (ER) stress, hypoxia, and the availability of nutrients, particularly glucose. The ER degradation enhancing alpha-mannosidase like protein 1 (EDEM1) is involved in ER-associated degradation (ERAD) targeting misfolded glycoproteins for degradation in an N-glycan-independent manner. EDEM1 was also identified as a new modulator of insulin synthesis and secretion.
View Article and Find Full Text PDFEfficacy of a Supervised Exercise Program on Pain, Physical Function, and Quality of Life in Patients With Breast Cancer: Protocol for a Randomized Clinical Trial.
JMIR Res Protoc
March 2025
Paseo de los Encomendadores, Faculty of Health Sciences, University of Burgos, Burgos, Spain.
Background: Breast cancer is the second most common cancer in women worldwide. Treatments for this disease often result in side effects such as pain, fatigue, loss of muscle mass, and reduced quality of life. Physical exercise has been shown to effectively mitigate these side effects and improve the quality of life in patients with breast cancer.
View Article and Find Full Text PDFClinical phenotypes and outcomes associated with respiratory syncytial virus infection in critically ill patients: a retrospective multicentre cohort study in Great Paris area hospitals, 2017-2023.
J Infect Dis
March 2025
Service de Médecine Intensive Réanimation, Hôpitaux Universitaires Henri Mondor - Albert Chenevier, Assistance Publique-Hôpitaux de Paris (AP-HP), 94010 Créteil, France.
Background: Respiratory syncytial virus (RSV) is one of the deadliest respiratory viruses. There is a need to better identify prognostic factors in RSV-infected patients, particularly those requiring intensive care unit (ICU) admission, with a focus on immunosuppressed patients.
Methods: Multicenter, retrospective cohort study of RSV-infected adults hospitalized in 17 ICUs in the Great Paris area between 08/01/2017 and 05/01/2023.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!