Objectives: The primary aim of this study is to evaluate protein-energy wasting in haemodialysis patients and assess their adherence to renal-specific guidelines.
Design: An observational cross-sectional study.
Setting: Patients were recruited from four major governmental hospitals in Amman, Jordan; The University of Jordan Hospital; Al-Hussain Medical Center, Al-Basheer Hospital; and Prince Hamzah Hospital. Data were collected during the period between January 2022 and January 2023.
Participants: The sample consisted of 344 adult patients who were above the age of 18 years with end-stage renal disease and undergoing haemodialysis.
Outcome Measures: Anthropodermic measurements were performed, and biochemical and dietary data were collected during dialysis sessions.
Results: The occurrence of protein-energy wasting, as indicated by a low albumin level (<40 g/L), was 59.6%. The intakes of most of the nutrients were significantly lower than the recommended corresponding values except for fat, where average consumption was significantly higher than the recommended dietary intakes (33.8%, p value=0.000). Mean protein and calorie intakes were associated with serum albumin levels (p value=0.003 and 0.044, respectively). 70% of the study participants revealed that they have rarely or never been spoken to regarding the importance of a renal-specific diet by their healthcare provider. Among study participants, 24% faced a great level of difficulty in following dietary recommendations, and approximately 15% indicated their inability to follow any recommendations.
Conclusion: Dietary intake was not adequate according to the dietary guidelines for haemodialysis patients, which could contribute to their low albumin levels and augment the risk of protein-energy wasting. Haemodialysis patients may experience defective nutritional care and a reduced level of commitment to dietary recommendations.
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http://dx.doi.org/10.1136/bmjopen-2024-094530 | DOI Listing |
Protein-energy wasting (PEW) facilitates major adverse clinical outcomes in chronic renal failure (CRF), with current therapies not suitable for all patients. Faecalibacterium prausnitzii (F. prausnitzii) can alleviate chronic kidney disease, with unclear effects and mechanisms on CRF with PEW.
View Article and Find Full Text PDFBMJ Open
March 2025
Department of Nutrition and Food Technology, The University of Jordan, Amman, Jordan.
Objectives: The primary aim of this study is to evaluate protein-energy wasting in haemodialysis patients and assess their adherence to renal-specific guidelines.
Design: An observational cross-sectional study.
Setting: Patients were recruited from four major governmental hospitals in Amman, Jordan; The University of Jordan Hospital; Al-Hussain Medical Center, Al-Basheer Hospital; and Prince Hamzah Hospital.
Int J Nephrol
February 2025
Department of Nephrology, Kasturba Medical College Manipal, Manipal Academy of Higher Education, Manipal 576104, Karnataka, India.
The increasing prevalence of elderly patients with end-stage kidney disease (ESKD) poses unique challenges in nephrology. These patients often present with multiple comorbidities, cognitive impairments, and frailty, which significantly impact treatment options and outcomes. Conservative kidney management (CKM) offers a viable alternative to dialysis for many elderly patients by focusing on symptom management and enhancing quality of life rather than merely prolonging life.
View Article and Find Full Text PDFJ Ren Nutr
February 2025
Department of Intensive Care Medicine, Sapporo Medical University School of Medicine, S1 W16, Chuo-ku, Sapporo, Japan.
Objective: Amino acid and protein loss during continuous renal replacement therapy (CRRT) has been proposed to contribute to protein energy wasting (PEW) in patients with acute kidney injury (AKI); however, the actual amount removed remains unclear. We investigated the loss of amino acids and proteins in the filtrate during CRRT in patients who did not receive nutritional supplementation.
Methods: A total of 19 patients with AKI who received low-dose continuous venovenous hemofiltration (CVVH) were included.
Clin Kidney J
January 2025
Division of Nephrology, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Background: Amino acid (AA) depletion during dialysis deteriorates the protein-energy status of haemodialysis (HD) patients. This study aimed to determine whether intradialytic amino acid (IDAA) replacement by continuous infusion versus acute load could provide better nutritional outcomes.
Methods: HD patients with mild protein-energy wasting, defined as a serum albumin level of 3.
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