An integrated frozen elephant trunk with a four-branched vascular graft may shorten the circulatory arrest time during open distal anastomosis. We report a case of acute type A aortic dissection where postoperative graft kinking led to acute liver failure, kidney injury and lower limb ischaemia corrected by thoracic endovascular aortic repair.
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http://dx.doi.org/10.1093/icvts/ivaf052 | DOI Listing |
Neurobiol Dis
March 2025
Department of Neurology, The First Affiliated Hospital with Nanjing Medical University, No. 300 Guangzhou Road, Nanjing 210029, China. Electronic address:
Objective: The loss of locus coeruleus (LC)-norepinephrine system may contribute to freezing of gait (FOG) in Parkinson's disease (PD), but free-water (FW) imaging has not been applied to investigate LC microstructural degeneration in FOG. This study was to investigate the role of the LC-norepinephrine system in FOG pathophysiology using FW imaging and resting-state functional magnetic resonance imaging.
Methods: FW metrics of LC were analyzed in 52 healthy controls, 79 PD patients without FOG (Non-FOG), and 110 PD patients with FOG (48 "Off-period" FOG and 62 "Levodopa unresponsive" FOG).
Expert Rev Pharmacoecon Outcomes Res
March 2025
Department of Human Neurosciences, Sapienza University, Rome, Italy.
Introduction: This systematic review and meta-analysis aimed to evaluate validated tools for assessing FOG in individuals with PD, focusing on their psychometric properties, linguistic adaptations, and methodological quality.
Methods: A systematic search was conducted across MEDLINE, CINHAL, SCOPUS, and Web of Science, following PRISMA-COSMIN guidelines. Studies assessing validity, reliability, and cross-cultural adaptation of FOG-specific tools were included.
Nat Commun
March 2025
National Tibetan Plateau Data Center, State Key Laboratory of Tibetan Plateau Earth System, Environment and Resource, Institute of Tibetan Plateau Research, Chinese Academy of Sciences, Beijing, China.
Thermokarst lakes, serving as significant sources of methane (CH), play a crucial role in affecting the feedback of permafrost carbon cycle to global warming. However, accurately assessing CH emissions from these lakes remains challenging due to limited observations during lake ice melting periods. In this study, by integrating field surveys with machine learning modeling, we offer a comprehensive assessment of present and future CH emissions from thermokarst lakes on the Tibetan Plateau.
View Article and Find Full Text PDFBiodivers Data J
February 2025
Department of Biology and Biotechnologies "Charles Darwin", Sapienza University, Rome, Italy Department of Biology and Biotechnologies "Charles Darwin", Sapienza University Rome Italy.
Background: The location and palaeoceanographic history of the Mediterranean Sea make it a biodiversity hotspot, prompting extensive studies in this region. However, despite the marine biodiversity of this area being apparently widely studied, a large amount of distributional data for Mediterranean taxa is still unpublished or scattered in various sources and formats, causing severe limitations to their potential reuse. This emerges as a particularly thorny issue for highly biodiverse and neglected taxa, such as invertebrates.
View Article and Find Full Text PDFBrain Res
March 2025
Department of Computer Science, Zhejiang Normal University, Jinhua, China. Electronic address:
The immersive experience provided by our approach empowers researchers with an intuitive exploration of brain structures. Within the brain's central nervous system, encompassing both white and gray matter, symptoms associated with Alzheimer's disease (AD) often manifest through gray matter decline. The manual identification of these changes proves to be a time-intensive endeavor.
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