This case report describes the use of photobiomodulation (PBM) as a complementary therapy in a 45-year-old patient with mammary tuberculosis (TB). The patient received conventional treatment, including antibiotic therapy and analgesics. Three months after the diagnosis, breast pain persisted (Visual Analog Scale [VAS] score: 8), and the mammary lesions had not healed. Adjuvant treatment with PBM (660 nm and 808 nm lasers, 100 mW, 3,333 mW/cm2, 20 J per session) was performed over 12 sessions in 38 days. After four PBM sessions, the patient reported no pain (VAS score: 0) and stopped using analgesics. Complete healing of the mammary lesions was observed after 12 sessions. The use of PBM was associated with improvements in tissue repair, pain control, and healing of lesions resulting from mammary TB.
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http://dx.doi.org/10.4269/ajtmh.24-0499 | DOI Listing |
J Immunol
February 2025
Department of Biomedical and Molecular Sciences, Queen's University, Kingston, ON, Canada.
Endometriosis is a chronic disorder in which endometrial-like tissue presents outside the uterus. Patients with endometriosis have been shown to exhibit aberrant immune responses within the lesion microenvironment and in circulation which contribute to the development of endometriosis. Thymic stromal lymphopoietin (TSLP) is an alarmin involved in cell proliferation and the induction of T helper 2 (Th2) inflammation in various diseases, such as asthma, atopic dermatitis, and pancreatic and breast cancer.
View Article and Find Full Text PDFIndian J Otolaryngol Head Neck Surg
January 2025
Department of Obstetrics and Gynecology, Apollo Medical Centre, Dar es Salaam, Tanzania.
Unlabelled: The jaws are affected secondarily by metastasis from a distant site. Metastatic lesions of jaws are very rare and constitute about 1% of all the malignancies occurring in the jaw, and the pattern of metastasis differs by age and sex. The objective of this review was to analyze the pattern of metastatic jaw lesions and its outcome.
View Article and Find Full Text PDFEur J Nucl Med Mol Imaging
March 2025
Physics and Instrumentation, Department of Radiology, University of Pennsylvania, Philadelphia, PA, US.
Purpose: Long-axial field-of-view PET scanners capture multi-organ tracer distribution with high sensitivity, enabling lower dose dynamic protocols and dual-tracer imaging for comprehensive disease characterization. However, reducing dose may compromise data quality and time-activity curve (TAC) fitting, leading to higher bias in kinetic parameters. Parametric imaging poses further challenges due to noise amplification in voxel-based modelling.
View Article and Find Full Text PDFAcad Radiol
March 2025
Department of Radiology, The Affiliated Huai'an Clinical College of Xuzhou Medical University, Huai'an, Jiangsu Province, China (Q.W., C.-C.H., H.-W.X., G.-J.B.). Electronic address:
Rationale And Objectives: Accurate determination of human epidermal growth factor receptor 2 (HER2) expression is critical for guiding targeted therapy in breast cancer. This study aimed to develop and validate a deep learning (DL)-based decision-making visual biomarker system (DM-VBS) for predicting HER2 status using radiomics and DL features derived from magnetic resonance imaging (MRI) and mammography (MG).
Materials And Methods: Radiomics features were extracted from MRI, and DL features were derived from MG.
Radiology
March 2025
From the Departments of Radiology (J.V.H., T.A., C.E.C., N.N., M.S.J., J.S.S.) and Epidemiology and Biostatistics (G.P.W.), Memorial Sloan Kettering Cancer Center, New York, NY.
Background Contrast-enhanced mammography (CEM) is an emerging modality that generates low-energy (LE) images that are visually equivalent to full-field digital mammography (FFDM) and recombined images that show lesion vascularity such as MRI. Supplemental whole-breast US increases cancer detection rates when performed with FFDM but not with MRI. Purpose To compare the performance of CEM, LE images, and LE images supplemented with whole-breast US in breast cancer detection during screening.
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