We assessed incremental completion of tuberculosis preventive treatment cascade in household contacts by offering services in community settings. This improved clinical evaluation by 12.4 (95% CI:11.7-13.0) percentage points (pp), treatment completion by 11.6 (95% CI: 10.6-12.7) pp, and cascade completion by 5.9 (95% CI: 5.1-6.7) pp.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1093/cid/ciaf088 | DOI Listing |
J Genet Eng Biotechnol
March 2025
Programa de Pós-Graduação em Ciências da Saúde, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil; Programa de Pós-Graduação em Parasitologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil. Electronic address:
Leprosy remains a significant health concern, particularly in India, Brazil, and Indonesia. Early diagnosis is essential to prevent complications, highlighting the need for improved diagnostic tools. This study aimed to identify novel Mycobacterium leprae antigens and assess their effectiveness against human sera through immunotools for antibody response evaluation.
View Article and Find Full Text PDFZhong Nan Da Xue Xue Bao Yi Xue Ban
October 2024
Department of Prevention and Treatment, Hunan Institute for Tuberculosis Control (Hunan Chest Hospital), Changsha 410013, China.
Objectives: Reducing mortality during anti-tuberculosis treatment is crucial for completing full-course standardized therapy and achieving tuberculosis cure. The study aims to analyze the mortality and its influencing factors among pulmonary tuberculosis patients undergoing anti-tuberculosis treatment in Hunan Province.
Methods: In this retrospective cohort study, data on pulmonary tuberculosis patients from the Hunan Provincial Tuberculosis Management Information System were collected between January 1, 2019 and December 31, 2023.
Int J Pharm
March 2025
Department of Mechanical Engineering, University of Alberta, Edmonton, AB, Canada.
Laboratory-scale spray drying can be a useful tool in developing new dry powder formulations for the delivery of biologics such as therapeutic proteins or vaccines. Low-temperature drying is often used in these processes to prevent the exposure of biologics to harsh conditions that could potentially lead to degradation or instability of the final product. However, low-temperature drying on small-scale equipment can result in very low production rates that may not be practical for generating sufficient material for studies requiring larger sample quantities, such as key preclinical or toxicology studies.
View Article and Find Full Text PDFFront Public Health
March 2025
Department of Clinical Epidemiology, Grenoble Alps University Hospital, La Tronche, France.
Multicultural Amazonian populations in remote areas of French Guiana face challenges in accessing healthcare and preventive measures. They are geographically and administratively isolated. Health mediation serves as an interface between vulnerable people and the professionals involved in their care.
View Article and Find Full Text PDFCampbell Syst Rev
March 2025
Liverpool School of Tropical Medicine, International Public Health Liverpool UK.
This is the protocol for a Campbell systematic review. The objectives are as follows. The primary objective of this systematic review is to evaluate and synthesise both published and unpublished literature on the effectiveness of sexual and reproductive health blended learning approaches for capacity strengthening of healthcare practitioners in LMICs.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!