Scrub typhus is a common but underrecognized cause of fever in the Asia-Pacific region. This review is the first to examine the history of scrub typhus in the context of notable historical events in Indonesia. Scrub typhus was first observed in 1902 and has since been documented through colonial and modern times. However, the available evidence is sparse. This lack of data is influenced by wider factors, including geopolitical climate and socio-economic factors. During the colonial era and World War II, research focused on economic and military interests. There were research gaps during the unstable period following independence in 1945. More research commenced only in the 1970s, mainly under the auspices of the Ministry of Health. Since 2000, there have been sporadic attempts to study scrub typhus on several major islands (Java, Sumatra, Sulawesi, Borneo, Bali). We found 51 relevant articles documenting the presence of the pathogen and its vectors, with only a single case confirmed with standard laboratory testing. This lack of data, combined with low awareness and diagnostic capacity, makes it difficult for policymakers to appreciate the impact of scrub typhus. Indonesia needs sustainable and continuous surveillance systems, infrastructure and research funding to ensure diseases of public health importance are not neglected.
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http://dx.doi.org/10.1093/trstmh/traf017 | DOI Listing |
Infez Med
March 2025
Department of Infectious Diseases, KIMSHEALTH, Thiruvananthapuram, Kerala, India.
Background: Scrub typhus, a mite-borne infection caused by , is endemic in South and Southeast Asia, including India. Although increasing awareness and improved healthcare access have reduced mortality, the disease remains a significant public health concern. Kerala, a southern Indian state, has reported scrub typhus cases for decades; however, comprehensive data on its clinical profile and severity indicators are limited.
View Article and Find Full Text PDFInfect Dis Model
June 2025
Ganzhou Center for Disease Control and Prevention, Ganzhou, 341000, Jiangxi, China.
Scrub typhus poses a serious public health risk globally. Forecasting the occurrence of the disease is essential for policymakers to develop prevention and control strategies. This study investigated the application of modelling techniques to predict the occurrence of scrub typhus and establishes an early warning system aimed at providing a foundational reference for its effective prevention and control.
View Article and Find Full Text PDFTravel Med Infect Dis
March 2025
Second Department of Infectious Disease, Kunming Children's Hospital, Kunming, Yunnan, China; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, Yunnan, China. Electronic address:
BMC Vet Res
March 2025
Department of Mizo, Mizoram University, Aizawl, Mizoram, 796004, India.
Background & Objectives: Orientia tsutsugamushi, a bacterial pathogen of scrub typhus, is transmitted to humans through the bite of infected chigger mites, and rodents are the natural hosts of the disease vector. The traditional practices of the tribal ethnic groups (Mizo) of Mizoram state such as capturing and consumption of rat meat collected from the agricultural fields could be one source of vector-disease transmission route. The present study aimed to detect and identify the pathogen of scrub typhus from vectors collected from rice field rats which were captured by farmers for meat consumption purposes.
View Article and Find Full Text PDFJ Vector Borne Dis
February 2025
Department of Microbiology, Government Medical College, Amritsar, India.
Background Objectives: India is both a tropical and subtropical region, where common causes of acute undifferentiated febrile illness (AUFI) include malaria, dengue fever, chikungunya fever, enteric fever, leptospirosis, scrub typhus, and Japanese encephalitis. These illnesses contribute significantly to patient morbidity and mortality, although the exact burden of each infection varies regionally. Given the high prevalence of these tropical diseases, prioritizing differential diagnoses in cases of AUFI is crucial.
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