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[Extra-pulmonary metastatic Ewing sarcoma: The French GroupOs diagnostic and therapeutic recommendations].
Bull Cancer
March 2025
Oncologie médicale, Institut Curie, Paris, France.
Patients who develop Ewing sarcoma with extra-pulmonary metastasis have a poor prognosis. A recent French protocol, CombinaiR3, was set up to evaluate the efficacy of induction chemotherapy followed by high-dose chemotherapy and metronomic maintenance treatment. It is now closed for inclusions and while waiting for the results, we propose a French consensus guideline for the management of patients diagnosed with Ewing sarcoma with extra-pulmonary dissemination.
View Article and Find Full Text PDFConsensus statement on pain management for pregnant patients with opioid use disorder from the Society for Obstetric Anesthesia and Perinatology, Society for Maternal-Fetal Medicine, and American Society of Regional Anesthesia and Pain Medicine.
Am J Obstet Gynecol
March 2025
Friends Research Institute, Baltimore, MD.
Pain management in pregnant and postpartum people with an opioid use disorder requires a balance among the risks associated with opioid tolerance, including withdrawal or return to opioid use, considerations around the social needs of the maternal-infant dyad, and the provision of adequate pain relief for the birth episode that is often characterized as the worst pain a person will experience in their lifetime. This multidisciplinary consensus statement from the Society for Obstetric Anesthesia and Perinatology, the Society for Maternal-Fetal Medicine, and the American Society of Regional Anesthesia and Pain Medicine provides a framework for pain management in obstetrical patients with opioid use disorder. The purpose of this consensus statement is to provide practical and evidence-based recommendations and is targeted to healthcare providers in obstetrics and anesthesiology.
View Article and Find Full Text PDFBest Practices for Imaging of Transcatheter Valve Failure: An Update From the Heart Valve Collaboratory.
J Am Coll Cardiol
March 2025
Cedars Sinai Medical Center, Los Angeles, California, USA. Electronic address:
This updated Heart Valve Collaboratory framework addresses the growing concern for transcatheter valve failure (TVF) following transcatheter aortic valve replacement (TAVR). With the increasing volume of redo-TAV and surgical TAV explantation, there is a critical need for standardized pathways and protocols for evaluating TVF using echocardiography and cardiac computed tomography (CT) angiography. This document clarifies prior definitions of bioprosthetic valve deterioration and bioprosthetic valve failure in a practical, imaging directed context for TAVR.
View Article and Find Full Text PDFThe strange adolescent world that complicates general practitioner prevention: a qualitative study.
BJGP Open
March 2025
Department of General Practice, University of Montpellier, Campus Arnaud de Villeneuve, Montpellier, France.
Background: Prevention is important in the international primary care system. In adolescents, several prevention areas need to be addressed: sexual health, mental health, substance use and addiction, physical activity, screen use, and social relationships..
View Article and Find Full Text PDFMeta-analyses of the global impact of non-antibiotic feed additives on livestock performance and health.
J Adv Res
March 2025
The Roslin Institute, University of Edinburgh, Edinburgh EH25 9RG, UK; College of Animal Science and Technology, Northwest A & F University, Yangling 712100, PR China. Electronic address:
Introduction: The impact of non-antibiotic feed additives on livestock performance and health is contingent upon a multitude of variables, including the animal species, dosage and type of feed additives, and duration of oral administration. However, there is a paucity of knowledge regarding the relationship between these factors and the performance of livestock animals.
Objectives: The objective of this study was to conduct a global meta-analysis based on a pool of empirical studies to investigate the effects of dietary additives on growth, production, blood metabolites, immunity, intestinal morphology, and the abundance of gut microbiota in livestock.
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