Background: Dermal fillers have been a popular choice for cosmetic dermatology procedures, and understanding the physical properties of microparticles used in dermal fillers is crucial for developing safe and effective aesthetic treatments.
Aim: This study analyzed three dermal filler products (Radiesse, HarmonyCA, and Hydroxyfill) based on calcium hydroxyapatite microspheres approved for dermal filler procedures in Mexico.
Material And Methods: The study used scanning electron microscopic analysis to study the morphology and characteristics of the calcium hydroxyapatite microspheres used in these dermal filler products.
Results: Results revealed important differences in the shape of the microspheres between the three products, which may have implications for their biocompatibility and performance in clinical use.
Conclusions: Gaining a deeper understanding of these differences enables the improved development of dermal fillers to meet the growing demand for safe and effective aesthetic treatments. This study contributes to building knowledge about the use of microparticles in soft tissue fillers for aesthetic treatments and medical applications.
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http://dx.doi.org/10.1111/jocd.70100 | DOI Listing |
J Cosmet Dermatol
March 2025
Division in Anatomy and Developmental Biology, Department of Oral Biology, Human Identification Research Institute, BK21 Four Project, Yonsei University College of Dentistry, Seoul, Korea.
Background: The selection of dermal fillers in aesthetic medicine often relies on factors such as cost, immediate outcomes, and practitioner experience. However, incorporating knowledge of fillers' rheological properties, such as viscoelasticity and cohesiveness, allows for more precise product selection tailored to patient needs and treatment goals while reducing the risk of complications.
Aims: This review aims to summarize essential considerations for filler selection, focusing on rheological properties, safety profiles, and clinical applications.
J Pharm Bioallied Sci
December 2024
Department of Clinical Dental Sciences, Ajman University, Ajman, United Arab Emirates.
Dentists' role in facial esthetics is growing, with advancements in cosmetic procedures, such as Botox and dermal fillers. Understanding the range of practitioners and their professional backgrounds is crucial for addressing risks. Data collection and analysis was done to retrieve scholarly papers using databases, such as PubMed and advanced Google search, and analyze.
View Article and Find Full Text PDFBackground: Hyaluronic acid (HA) fillers offer an advantage in being easily reversible with enzymatic hyaluronidase administration. Yet, there are no clear guidelines regarding the amount of hyaluronidase that should be administered given that commercially available fillers differ in constituent properties.
Methods: Six HA fillers were mixed with aliquots of human recombinant hyaluronidase (0 mL, 0.
J Cosmet Dermatol
March 2025
Centro de Investigación Científica de Yucatán, Mérida, Yucatán, Mexico.
Background: Dermal fillers have been a popular choice for cosmetic dermatology procedures, and understanding the physical properties of microparticles used in dermal fillers is crucial for developing safe and effective aesthetic treatments.
Aim: This study analyzed three dermal filler products (Radiesse, HarmonyCA, and Hydroxyfill) based on calcium hydroxyapatite microspheres approved for dermal filler procedures in Mexico.
Material And Methods: The study used scanning electron microscopic analysis to study the morphology and characteristics of the calcium hydroxyapatite microspheres used in these dermal filler products.
J Cosmet Dermatol
March 2025
Department of Dermatology, Razi Hospital, Tehran University of Medical Sciences (TUMS), Tehran, Iran.
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