Purpose: To report a case of rhegmatogenous retinal detachment (RRD) caused by spontaneous retinal dialysis in intermediate uveitis due to multiple sclerosis (MS).
Observations: A 29-year-old Middle Eastern female, was diagnosed with MS following an episode of bilateral intermediate uveitis. Later, she presented with sequential RRD in both eyes. The patient underwent a 25-gauge pars plana vitrectomy. Intraoperatively, retinal dialysis was noted due to traction at the vitreous base. Peripheral retinal thinning due to ischemia was also noted. Postoperatively, she recovered her visual acuity in both eyes to 6/6.
Conclusions And Importance: We describe a case of bilateral RRD caused by spontaneous retinal dialysis in intermediate uveitis secondary to MS. Retinal detachment was managed by conventional vitrectomy and tamponading agent. We suggest looking for traction at the vitreous base in cases of intermediate uveitis secondary to MS.
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http://dx.doi.org/10.1016/j.ajoc.2025.102277 | DOI Listing |
Am J Ophthalmol Case Rep
June 2025
Department of Ophthalmology, Hamad Medical Corporation, Doha, Qatar.
Purpose: To report a case of rhegmatogenous retinal detachment (RRD) caused by spontaneous retinal dialysis in intermediate uveitis due to multiple sclerosis (MS).
Observations: A 29-year-old Middle Eastern female, was diagnosed with MS following an episode of bilateral intermediate uveitis. Later, she presented with sequential RRD in both eyes.
BMJ Open Ophthalmol
February 2025
Department of Ophthalmology, National Defense Medical College, Tokorozawa, Saitama, Japan
Introduction: Rho-associated protein kinases (ROCKs) are a key regulator of T cell function, influencing a wide range of processes from activation to differentiation. Experimental autoimmune uveoretinitis (EAU) is an animal model of human non-infectious uveitis. This study aimed to evaluate the suppressive effects of ripasudil, a ROCK inhibitor, on ocular inflammation when administered from the onset of EAU and to elucidate the underlying mechanisms of its inhibitory effects.
View Article and Find Full Text PDFCase Rep Ophthalmol Med
February 2025
Department of Ophthalmology & Visual Sciences, SUNY Upstate Medical University, Syracuse, New York, USA.
Sarcoidosis is a systemic inflammatory disease associated with ocular involvement in 20%-30% of cases. The current gold standard for detecting sarcoidosis is computed tomography of the thorax, which is 73% sensitive. Definitive diagnosis necessitates biopsy, with Schaumann bodies and non-necrotizing granulomas serving as key pathological hallmarks.
View Article and Find Full Text PDFCureus
January 2025
Department of Ophthalmology, Hospital Tuanku Ja'afar, Seremban, MYS.
Anterior uveitis frequently occurs in ocular cytomegalovirus (CMV) infection among immunocompetent individuals. Here, we report a rare instance of bilateral isolated intermediate uveitis without retinitis or retinal vasculitis in an immunocompetent individual, later confirmed to be an ocular CMV infection. He was treated with systemic ganciclovir and topical corticosteroid.
View Article and Find Full Text PDFOcul Immunol Inflamm
February 2025
Department of Ophthalmology, Erciyes University Medical Faculty, Kayseri, Turkey.
Purpose: To present the clinical manifestations, ocular complications and treatment results of pediatric pars planitis (PPP).
Methods: This retrospective clinical study was conducted at a tertiary care center and included 28 children (51 eyes) aged 16 years or younger. Visual acuity (VA), anterior chamber cell (ACC) grade, vitritis grade, central macular thickness (CMT), fundus fluorescein angiography (FFA) score, treatment approach, complications, and relapse rate were recorded.
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