Purpose: CPAP is the standard treatment for obstructive sleep apnea (OSA), but as many as 50% of patients discontinue its use, within three years. The PROTEUS project aims to enhance CPAP adherence through telemonitoring.
Patients And Methods: OSA patients undergoing CPAP treatment since July 2018, had an in-person reassessment after three months, followed by quarterly telemonitoring by providers, who intervened in cases of poor adherence (less than 4 h·night or less than 70% of days), excessive mask leakage, or elevated residual apnea-hypopnea index (rAHI).
Results: A total of 486 (~87%) out of 558 patients analyzed remained adherent to CPAP after five years. The average rAHI was 3.95 ± 5.25 events·h, the average CPAP usage was 6.35 ± 1.72 hours. Elevated mask leakage occurred in 25% of patients. No significant differences were found between sexes.
Conclusion: The PROTEUS project showed promising results in supporting long-term CPAP adherence. However, further research is needed to validate its long-term impact and wider applicability in OSA management.
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http://dx.doi.org/10.2147/NSS.S501341 | DOI Listing |
Nat Sci Sleep
February 2025
Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy.
Purpose: CPAP is the standard treatment for obstructive sleep apnea (OSA), but as many as 50% of patients discontinue its use, within three years. The PROTEUS project aims to enhance CPAP adherence through telemonitoring.
Patients And Methods: OSA patients undergoing CPAP treatment since July 2018, had an in-person reassessment after three months, followed by quarterly telemonitoring by providers, who intervened in cases of poor adherence (less than 4 h·night or less than 70% of days), excessive mask leakage, or elevated residual apnea-hypopnea index (rAHI).
Antioxidants (Basel)
January 2025
Department of Agricultural Science and Food Engineering, "Lucian Blaga" University of Sibiu, 7-9 Dr. Ion Ratiu, 550024 Sibiu, Romania.
The presence of bioactive compounds in plants with red flowers constitutes a valuable natural resource for the food, pharmaceutical, and medical industries. This paper aims to highlight these characteristics to facilitate the selection of extracts according to market needs. The analyzed parameters can provide valuable insights into the compositional variability of the five red flower plants, as new sources of bioactive compounds and natural antioxidants of plant origin.
View Article and Find Full Text PDFAntibiotics (Basel)
January 2025
Chemistry Interdisciplinary Project (ChIP) Research Center, School of Pharmacy, University of Camerino, Via Madonna delle carceri, 62032 Camerino, Italy.
: Plants species of the genus are traditionally used to treat prostatitis and other urinary tract disorders and are particularly rich in ellagitannins and flavonol 3--glycosides. The aim of this work was to evaluate the inhibitory activity of different extracts from L. and Schreb.
View Article and Find Full Text PDFRes Nurs Health
February 2025
Department of Anesthesiology and Reanimation, Faculty of Medicine, İzmir Katip Çelebi University, İzmir, Türkiye.
This study aimed to determine microbial colonization in indwelling urinary catheters (UCs) and identify patient-specific risk factors associated with this colonization. This cross-sectional study involved 61 hospitalized intensive care unit patients with indwelling UCs. Bacterial colonization and susceptibility were assessed in the indwelling UCs from the second day onwards following urinary catheterization.
View Article and Find Full Text PDFVet Res
February 2025
National Key Laboratory of Agricultural Microbiology, Hubei Hongshan Laboratory, Huazhong Agricultural University, Wuhan, 430070, Hubei, China.
Sow endometritis is usually caused by multiple species of pathogenic bacteria. Numerous isolates from endometritis patients have developed antimicrobial resistance. Thus, novel antibacterial agents and strategies to combat endometritis are needed.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!