Objectives: This study aimed to enhance the quality of Advanced Cardiac Life Support (ACLS) training, with quality defined as the combination of technical skills (TS) and non-technical skills (NTS), by addressing the gap in effective methods for developing NTS through simulation-based medical education (SBME). Specifically, it sought to develop and evaluate a strategy for establishing shared mental models (SMM) and fostering trust among team members during undergraduate emergency training.
Methods: This study was conducted during mandatory ACLS undergraduate simulation training sessions. The control group participated in traditional, teacher-led classes and debriefings, while the intervention group received training incorporating SMM as the intervention. The study evaluated the quality of cardiopulmonary resuscitation as the primary outcome, encompassing both TS and NTS. Additionally, changes in undergraduate situational motivation, assessed within the framework of self-determination theory, and subjective learning gains were analyzed.
Results: The control group demonstrated a significant improvement in TS ( = .030), while the intervention group did not ( = .078). Conversely, the intervention group showed a significant improvement in NTS ( = .01; 95% confidence interval [0.296, 2.17]), whereas the control group did not ( = .105). The motivational changes of both groups were comparable, reflecting high levels of autonomous motivation. Both groups also reported significant learning gains.
Conclusion: This study demonstrates that SBME is highly effective for teaching TS. However, it is crucial to incorporate advanced instructional methods focusing on NTS. One promising approach is the development of SMM. Based on our results, hands-on practice remains essential and should not be restricted to theoretical or conceptual training. A balanced combination of advanced didactic techniques and practical application ensures that learners develop both, TS and NTS. SBME and the development of SMM equally address both the motivational and content dimensions of learning, enhancing student engagement while effectively conveying essential knowledge and skills.
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http://dx.doi.org/10.1177/23821205251316749 | DOI Listing |
Ther Apher Dial
March 2025
Nephrology Blood Purification Center, The First Medical Center, Chinese People's Liberation Army General Hospital, Beijing, China.
Introduction: This study aimed to investigate the effect of intermittent hemodialysis filtration mode (IHDF) on intradialytic hypotension and nutritional status in patients with end-stage renal disease (ESRD).
Methods: Patients with ESRD who underwent hemodialysis and were treated at our hospital from December 2021 to December 2023 according to the inclusion and exclusion criteria were selected and randomly assigned into two groups: the experimental group (patients received intermittent hemodialysis filtration mode treatment, n = 50) and the control group (patients received conventional maintenance hemodialysis treatment, n = 49). Subsequently, the participant characteristics, the treatment effect, the occurrence of intradialytic hypotension, the safety assessment, blood pressure indicators, and the nutritional status were compared between the two groups.
Metab Syndr Relat Disord
March 2025
Center for Nutrition and Health Research, National Institute of Public Health, Cuernavaca, México.
Metabolic syndrome (MetS) is a clinical construct that conglomerates risk factors interconnected with cardiovascular diseases and type 2 diabetes. More than a thousand million individuals in the world were diagnosed with MetS in 2018. Our objective was to examine the prevalence of MetS and its components among Mexican adults.
View Article and Find Full Text PDFNanomedicine (Lond)
March 2025
Department of Chemistry and The Institute for Laser, Photonics, and Biophotonics, University at Buffalo, The State University of New York, Buffalo, NY, USA.
Background: Nanomedicine offers a number of innovative strategies to address major public health burdens, including complex respiratory illnesses. In this work, we introduce a multi-drug nanoparticle fabricated using femtosecond laser ablation for the treatment of influenza, SARS-CoV-2, and their co-infections.
Methods: The SARS-CoV-2 antiviral, remdesivir; the influenza antiviral, baloxavir marboxil; and the anti-inflammatory, dexamethasone, were co-crystalized and then ablated in aqueous media using a femtosecond pulsed laser and subsequently surface modified with the cationic polymer, chitosan, or poly-d-lysine.
J Anim Sci
March 2025
Department of Animal Sciences, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Yellow mealworms (Tenebrio molitor) serve as an alternative protein source. Because the amino acid (AA) concentrations, AA digestibility, and protein quality of ingredients may vary depending on their husbandry, harvest and processing procedures, and other factors, each should be evaluated separately. The objective of this study was to measure the AA composition, AA digestibility, and protein quality of yellow mealworm-based ingredients using the precision-fed cecectomized rooster assay.
View Article and Find Full Text PDFHaematologica
March 2025
Experimental Hematology, Vall d'Hebron Institute of Oncology (VHIO), Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain; Department of Medicine, Universitat Autònoma de Barcelona, Bellaterra.
Continuous treatment with ibrutinib not only exerts tumor control but also enhances T cell function in patients with chronic lymphocytic leukemia (CLL). We conducted longitudinal multi-omics analyses in samples from CLL patients receiving ibrutinib upfront to identify potential adaptive mechanisms to Bruton tyrosine kinase (BTK) inhibition during the first 12 months of continuous therapy. We found that ibrutinib induced a decrease in the expression of exhaustion markers and the proportion of Tregs and Tfh cells normalized to levels observed in healthy donors.
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