Introduction: Knowledge translation from research to clinical practice can often be challenging, and practice modification patterns among surgeons may stem from a variety of sources, including personal experience, peer influence, ongoing education, and evolving research findings.
Research Question: This study aimed to investigate the adoption patterns amongst surgeons for newer innovations and to analyse the factors affecting the implementation of the same in clinical practice. We used the adoption of osteobiologics as a case example.
Methods: An international expert survey was conducted among AO Spine users and members. The survey, comprising 30 items, explored surgeons' demographics, risk aversion, and factors influencing practice change. We categorized the innovation-adoptive nature of the surgeons and scored their risk-adoptive behaviour.
Results: A total of 458 responses were received from surgeons across 81 countries including 433 male (95%), orthopaedic surgeons (n = 263; 57%) from university-affiliated hospitals (n = 185; 40%). Most were in the early majority phase of the innovation-adoption cycle (n = 174; 38%) with a majority in the 'high-moderate' risk-adoption category (n = 396; 86%). This risk adoption behaviour had a significant correlation with their appetite for innovation (r = 0.182,p=<0.001). About 67.9% of respondents preferred scientific literature and conference presentations showcasing solid clinical evidence to be the most influential factor in driving change in their clinical practice. Material logistics (55%) is considered an important barrier to practice modification followed by familiarity (50%) and financial reimbursements (25%).
Discussion & Conclusion: A complex interplay exists between risk-adoptive behaviour amongst surgeons and the factors influencing a change in their clinical practice. Although most surgeons were in the early adoptive phase in accepting the innovations into their clinical practice, they were also equally noted to be risk tolerant. Hence, a successful adoption of practice-changing innovation hinges on addressing not only logistical and financial challenges but also on providing robust scientific evidence to drive the necessary change in clinical practice.
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http://dx.doi.org/10.1016/j.bas.2025.104206 | DOI Listing |
Hum Vaccin Immunother
December 2025
Sixth Form Department, Townley Grammar School, Bexleyheath, UK.
We explored adolescent viewpoints on vaccines and hesitancy using an anonymized, validated, self-completed electronic questionnaire amongst state-school Year 12-13 adolescents in London, UK. As the response rate was low (Cohort 1; = 112/486, 23.0%), we repeated the survey with incoming students (cohort 2, = 256/275; 93%).
View Article and Find Full Text PDFActa Anaesthesiol Scand
April 2025
Department of Anesthesiology and Intensive Care Medicine, Institute of Clinical Sciences at the Sahlgrenska Academy, University of Gothenburg and Section for Cardiothoracic Anesthesia and Intensive Care, Sahlgrenska University Hospital, Gothenburg, Sweden.
Background: Acute kidney injury (AKI) is a serious complication after lung transplantation, but the reported incidence varies in the literature. No data on AKI have been published from the Swedish lung transplantation program.
Methods: The aim of our study was to investigate the incidence, perioperative risk factors, and effects of early postoperative acute kidney injury (Kidney Disease Improving Global Outcomes [KDIGO] criteria) after lung transplantation.
Microbiol Immunol
March 2025
Niterra Co. Ltd., Japan.
Ambient humidity, temperature, and ozone influence the viability of airborne viruses, but their synergistic effects are poorly understood, particularly regarding ozone with humidity/temperature changes. Therefore, we examined the inactivation of airborne influenza viruses and coronaviruses under combinations of low ambient ozone concentrations, relative humidity (RH) levels, and temperatures typical of daily life. Viral fluid was atomized in a closed chamber conditioned with different combinations of these factors.
View Article and Find Full Text PDFPlant Physiol
March 2025
Shanghai Collaborative Innovation Center of Agri-Seeds, School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai 200240, China.
Sugar accumulation during fruit ripening is an essential physiological change that influences fruit quality. While NAC transcription factors are recognized for their role in modulating strawberry (Fragaria × ananassa) fruit ripening, their specific contributions to sugar accumulation have remained largely unexplored. This study identified FvNAC073, a NAC transcription factor, as a key regulator that not only exhibits a gradual increase in gene expression during fruit ripening but also enhances the accumulation of sucrose.
View Article and Find Full Text PDFObjectives: the impact of handgrip strength (HGS) on postoperative complications and long-term survival following hepatectomy in patients with primary liver cancer (PLC) remains unclear. This study aimed to evaluate the influence of HGS on postoperative complications and overall survival in patients with PLC.
Methods: in total, 298 patients with PLC who underwent liver resection were included in the prospective cohort study.
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