Background: This network meta-analysis (NMA) aimed to explore the impact of Non-pharmacological therapies (NPT) on alleviating primary dysmenorrhea (PD) symptoms and assess the effectiveness differences among various NPT.
Methods: We searched seven databases and summarized clinical trials of PD treated with NPT from inception to September 6, 2023. Randomized controlled clinical trials (RCTs) of PD treated with NPT. The outcomes were the Visual Analog Scale (VAS), the Cox menstrual symptom scale (CMSS), and response rate. Quality was assessed using the Cochrane risk of bias assessment tool. Pairwise meta-analysis and network meta-analysis (NMA) was performed by RevMan (5.4), Stata (15.0), and WinBUGS (1.4.3). The ranking probabilities for all treatment interventions were performed using the Surface Under the Cumulative Ranking curve (SUCRA).
Results: A total of 16 RCTs were finally included, involving 8 kinds of NPT. Results of pairwise meta-analyses: For the VAS score results, moxibustion (SMD: -0.591,95% CI: -0.916, -0.266) was more effective than acupuncture, acupuncture (SMD: -0.948,95% CI: -1.853, -0.044) was more effective than placebo, and yoga (SMD: 2.634,95% CI: -4.28, -0.988) was more effective than the blank control. NMA results: Compared to the blank control, acupuncture (SMD: -4.81; 95% CI: -6.63, -3.00), auricular point therapy (SMD: -4.36; 95% CI: -7.18, -1.60), yoga (SMD: -2.12; 95% CI: -3.13, -1.09), moxibustion (SMD:5.54; 95% CI: 3.33, 7.68), and placebo (SMD: 3.10; 95% CI: 1.03, 5.27) proved to be a superior reduction in VAS. The use of acupressure (SMD: 2.49; 95% CI: 0.03, 5.03), moxibustion (SMD: -2.45; 95% CI: -4.06, -0.71), and acupuncture (SMD: -1.72; 95% CI: -2.75, -0.56) demonstrated a greater decrease in VAS efficacy than placebo. The consolidated ranking outcomes indicate that moxibustion, acupuncture, and auricular acupoint therapy occupy high SUCRA positions across various outcome metrics.
Conclusion: Acupuncture, moxibustion and auricular point may be the best treatment for PD. In the future, more trials are needed to obtain higher-quality evidence and the best protocols.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11874745 | PMC |
| http://dx.doi.org/10.2147/JPR.S498184 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Critical Analysis of Reporting Quality of Network Meta-Analyses in Periodontology and Implantology.
Eur J Dent
March 2025
Department of Prosthodontics and Dental Implantology, College of Dentistry, King Faisal University, Al-Ahsa, Saudi Arabia.
The increasing recognition of network meta-analyses (NMAs) in dentistry, particularly in periodontology and implantology, lacks assessed reporting quality. To address this, our study will undertake a systematic review of previously reported NMAs. Researchers conducted an electronic search in Web of Science and Scopus to identify NMAs across all dentistry journals.
View Article and Find Full Text PDFSkeletal, dentoalveolar and soft tissue effects of different maxillary expansion appliances in cleft lip/palate patients: A systematic review and frequentist network meta-analysis.
J Stomatol Oral Maxillofac Surg
March 2025
BDS, MSc, Ph.D, associate professor, Department of Clinical Oral Health Sciences, College of Dental Medicine, QU Health, Qatar University, Doha, Qatar. Electronic address:
Introduction: This study aimed to assess the available evidence regarding the skeletal, dentoalveolar and soft tissue effects of different maxillary expansion appliances in cleft lip/palate patients.
Methods: We assessed the effects of different maxillary expansion appliances on skeletal structure and dentoalveolar and soft tissue in cleft lip/palate patients. We searched the PubMed, Science Direct, Web of Science, Cochrane, and LILACS databases through September 2024; that investigation was augmented by a manual search.
Network meta-analysis based ranking of dry off interventions to cure or prevent intramammary infections in dairy cows.
Prev Vet Med
March 2025
Infectious Disease Epidemiology, Wageningen University and Research, Wageningen 6700 AH, the Netherlands; Business Economics Group, Wageningen University and Research, Wageningen 6700 EW, the Netherlands. Electronic address:
This study aimed to rank dry off interventions for the prevention of new intramammary infections (IMI) and the cure of existing IMI in quarters of dry cows using two network meta-analyses. Randomized controlled trials reported in 137 papers were assessed for inclusion eligibility. Network meta-analyses were performed separately for the incidence risk of IMI and cure risk of IMI.
View Article and Find Full Text PDFEfficacy of digital therapeutic applications for cognitive training among older adults with mild cognitive impairment or dementia: A systematic review and network meta-analysis of randomized controlled trials.
Psychiatry Res
March 2025
Department of Biomedical Informatics, College of Medicine, Konyang University, Daejeon, 35365, Republic of Korea; Konyang Medical data Research group-KYMERA, Konyang University Hospital, Daejeon, Republic of Korea; Myunggok Medical Research Center, Konyang University Hospital, Daejeon, Republic of Korea. Electronic address:
Various digital therapeutics (DTx), which utilize computerized cognitive training (CCT) to improve cognitive functioning, have been tested and released. However, the efficacy of these DTx approaches may be diverse. This study aims to meta-synthesize the associations between mobile applications and cognitive functioning outcomes in older adults with mild cognitive impairment (MCI) or dementia from randomized controlled trials (RCTs).
View Article and Find Full Text PDFPurpose: To compare anesthesia techniques (WALANT (wide-awake anesthesia no tourniquet), locoregional anesthesia, local anesthesia with tourniquet or sedation) for carpal tunnel release (CTR).
Methods: A comprehensive literature search was conducted on PubMed, MEDLINE, Embase and the Cochrane Library up to May 2023. Two independent reviewers selected the studies and extracted the data.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!