Objective: This technical report describes a fully digital workflow for the manufacturing of a functional removable esthetic device (FRED) that addresses multiple clinical scenarios before prosthetic rehabilitation. The proposed method integrates advanced digital tools to achieve functional and esthetic outcomes while ensuring reversibility and patient comfort.
Clinical Considerations: The workflow includes intraoral and facial scanning, jaw motion tracking, and CAD/CAM technology to create a 4D virtual patient. This allows for a precise recording of the maxillomandibular relationship and facilitates the determination of the comfort position to establish a new occlusal vertical dimension (OVD). FRED is a custom-designed, removable, tooth-colored device manufactured to provide temporary functional support, esthetic preview, catering to different clinical scenarios, including tooth wear, occlusal trauma, and periodontal conditions.
Conclusions: This technique combines digital and traditional prosthetic principles into a patient-centered, adaptable workflow, allowing precise, non-invasive, and dynamic evaluation of OVD modifications. By integrating digital recording, facial scanning, and CAD/CAM fabrication, it enhances function, esthetics, and patient comfort.
Clinical Significance: This technique highlights the synergy of digital innovation and prosthetic principles, enhancing diagnostic capabilities and treatment predictability. The patient-centered design supports functional stability and esthetic outcomes, making it a valuable tool in modern prosthetic dentistry.
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http://dx.doi.org/10.1111/jerd.13454 | DOI Listing |
Int J Pharm
March 2025
Research Institute for Medicines (iMed.ULisboa), Faculdade de Farmácia, Universidade de Lisboa, Av. Prof. Gama Pinto, 1649-033 Lisboa, Portugal. Electronic address:
The pharmaceutical industry has been shifting towards continuous manufacturing, specifically for tablet production. Compared to batch processing, continuous tableting exhibits higher process efficiency, better process control, reduced footprint, and consistent product quality. Understanding mass flow variability and feed factor profile of raw materials in the loss-in-weight feeding process is essential for controlling continuous processes.
View Article and Find Full Text PDFZool Res
March 2025
Key Laboratory of Brain Cognition and Brain-inspired Intelligence Technology, Institute of Automation, Chinese Academy of Sciences, Beijing 100190, China.
Advancements in animal behavior quantification methods have driven the development of computational ethology, enabling fully automated behavior analysis. Existing multi-animal pose estimation workflows rely on tracking-by-detection frameworks for either bottom-up or top-down approaches, requiring retraining to accommodate diverse animal appearances. This study introduces InteBOMB, an integrated workflow that enhances top-down approaches by incorporating generic object tracking, eliminating the need for prior knowledge of target animals while maintaining broad generalizability.
View Article and Find Full Text PDFDent Clin North Am
April 2025
Clinic for Conservative Dentistry and Periodontology, LMU Klinikum, Munich, Germany; Institute of Dental Medicine, First Faculty of Medicine of the Charles University and General University Hospital in Prague, Prague, Czech Republic.
Artificial intelligence (AI) has significantly impacted numerous industries, including health care, dentistry, and specifically prosthodontics. This review focuses on AI's role in prosthodontics, detailing its use in diagnosis, design, and manufacturing. AI-driven systems analyze intraoral scans, improve prosthetic planning, and aid in robotic procedures.
View Article and Find Full Text PDFDent Clin North Am
April 2025
Department of Restorative Dentistry, Rutgers School of Dental Medicine, 110 Bergen Street, Room C-703, Newark, NJ 07103, USA. Electronic address:
Advancements in digital technologies over the past decade have revolutionized dentistry, particularly with the integration of digital workflows in removable partial dentures (RPDs). Key innovations include digital data capture and computer-aided design and manufacturing, which enhance patient comfort, streamline workflows, and reduce treatment time and costs. Initially embraced by fixed restorations, these technologies are now transforming RPDs, previously reliant on analog methods.
View Article and Find Full Text PDFJ Orofac Orthop
March 2025
Department of Orthodontics and Dentofacial Orthopedics, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Aßmannshauser Straße 4-6, 14197, Berlin, Germany.
Purpose: For the fabrication of an orthodontic mini-implant (OMI)-borne appliance, the position of the inserted OMI can be detected by a silicone impression or an intraoral scan (IOS). In case of digital planning, it can be taken over from the planning and the appliance can be produced in advance. This study aimed to evaluate the accuracy of these three techniques and whether there is an association with the insertion angle.
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