Purpose: To compare the wound healing, pain intensity and lumbar function in elderly patients with lumbar spinal stenosis after laminectomy decompression or percutaneous transforaminal endoscopic surgery.
Methods: A retrospective study was conducted on 65 patients who underwent laminotomy and 69 patients who underwent percutaneous transforaminal endoscopic spinal decompression surgery. clinical data analysis, including surgical parameters, complications, postoperative wound healing, pain intensity, lumbar function, and correlation analysis, was performed.
Results: The operative time of percutaneous transforaminal endoscopic surgery was significantly shorter than that of laminotomy (70.78±6.80 min vs 128.97±4.70 min, < 0.001), intraoperative blood loss was significantly reduced (94.22± 7.69ml vs 327.68± 6.44ml, < 0.001), postoperative wound healing time and time to get out of bed were significantly shortened, pain was reduced by visual analog scale (3.48±1.11 vs 2.80±1.05, = 0.007), the Japanese Orthopaedic Association (JOA) score was significantly increased, and the Oswestry Disability Index (ODI) score showed significantly decrease. The incidence of urinary tract infection and urinary retention was higher after laminotomy. Correlation analysis showed that operative time, intraoperative blood loss, and time to get out of bed were significantly related to prognosis in elderly patients.
Conclusion: Percutaneous transforaminal endoscopic surgery is significantly superior to conventional laminectomy decompression in the treatment of elderly lumbar spinal stenosis.
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http://dx.doi.org/10.1080/07853890.2025.2472865 | DOI Listing |
Background: Cold atmospheric plasma (CAP) has shown good clinical efficacy in treating chronic wounds, but its superiority over conventional treatment is still under debate. This meta-analysis systematically analyzed the clinical efficacy of CAP compared to control therapy.
Methods: Relevant literature was obtained online according to PRISMA guidelines.
Background: This study aimed to investigate the effects of total antioxidant capacity (T-AOC), superoxide dismu-tase (SOD), and malondialdehyde (MDA) in blood on the postoperative wound healing process of patients with severe burns treated by Meek micrografting.
Methods: In total, 154 patients with severe burns who underwent Meek micrografting treatment were selected as the observation group, and 80 healthy people were taken as the control group. General clinical data were collected, and serum T-AOC, SOD, and MDA were analyzed by biochemical analysis.
Adv Mater
March 2025
School of Life Sciences, Shandong First Medical University & Shandong Academy of Medical Sciences, Tai'an, 271016, China.
Diabetic wounds are a common complication of diabetes and pose a significant threat to human health. High glucose concentration in the wound remains a major obstacle, necessitating effective strategies to achieve sustained glucose consumption for synergistic diabetic wound therapy. In this study, an Au-based nanomaterial is developed that can adjust its morphology in different therapeutic processes.
View Article and Find Full Text PDFIndian J Otolaryngol Head Neck Surg
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Otorhinolaryngology and Head & Neck Surgery, Jain ENT Hospital, Jaipur, Rajasthan India.
The aim of this study was to observe the effect of topical application of manuka honey in healing of nasal mucosa in Post Endoscopic Sinus Surgery. A total of 50 patients were selected and were operated for sinonasal diseases. Post operative after nasal pack removal manuka honey was applied.
View Article and Find Full Text PDFRegen Ther
March 2025
Cellular and Molecular Research Center, Mazandaran University of Medical Sciences, Sari, Iran.
A diabetic wound is the most frequent form of chronic wound. Because diabetic wounds have multiple factors contributing to their development, the best treatments involve using a combination of approaches. Herein we assessed whether bioactive and degradable bioengineered micro-porous collagen-based three-dimensional scaffold (CTS) encapsulated with adipose mesenchymal stem cells (ASCs)-derived exosomes could accelerate the wound healing process in diabetic rats.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!