Adult spinal deformity (ASD) surgery aims to correct abnormal spinal alignment in both the sagittal and coronal planes to alleviate pain and improve functional activities of daily living. Despite the advancements in surgical techniques that have led to better clinical outcomes, postoperative mechanical complications remain. These complications include instrumentation failure, with proximal junctional kyphosis (PJK), proximal junctional failure (PJF), and rod fractures (RFs) being the most common. Such complications deteriorate clinical outcomes and often require revision surgery, which can be more burdensome for surgeons and patients, than index surgery. Thus, the risk factors for mechanical complications must be identified, and effective preventive strategies established. Therefore, this study aimed to review the risk factors for mechanical complications, focusing on PJK, PJF, and RF, and explore prevention strategies for these complications in ASD surgery, drawing upon recent literature.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.31616/asj.2024.0505 | DOI Listing |
Interdiscip Cardiovasc Thorac Surg
March 2025
Division of Cardiac Surgery, Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy.
Objectives: Differences in inflammatory responses between men and women may contribute to sex disparities in cardiac surgery outcomes. We investigated how sex differences influence systemic inflammatory response syndrome (SIRS) and adverse outcomes after cardiac surgery.
Methods: A single-center retrospective cohort study of patients undergoing cardiac surgery from 2018 to 2020 was performed.
Adv Mater
March 2025
Department of Chemistry, Hanyang University, Seoul, 04763, Republic of Korea.
Migration of implanted self-expandable metallic stent (SEMS) in the malignant or benign esophageal stricture is a common complication but not yet resolved. Herein, this research develops a hydrogel-impregnated robust interlocking nano connector (HiRINC) to ensure adhesion and reduce the mechanical mismatch between SEMSs and esophageal tissues. Featuring a network-like porous layer, HiRINC significantly enhances adhesion and energy dissipation during esophageal peristalsis by utilizing mechanical interlocking and increasing hydrogen bonding sites, thereby securing SEMS to tissues.
View Article and Find Full Text PDFCells
February 2025
Department of Anesthesiology, University of California, San Diego, CA 92093, USA.
A significant portion of adolescents suffer from mental illnesses and persistent pain due to repeated stress. The components of the nervous system that link stress and pain in early life remain unclear. Prior studies in adult mice implicated the innate immune system, specifically Toll-like receptors (TLRs), as critical for inducing long-term anxiety and pain-like behaviors in social defeat stress (SDS) models.
View Article and Find Full Text PDFCurr Opin Anaesthesiol
February 2025
Department of Orthopaedics and Trauma Surgery.
Purpose Of Review: Bleeding complications from pelvic injuries occur after high-energy trauma as well as after low-energy trauma in elderly patients and are the main contributors to mortality. Demographic changes necessitate focussing on both entities and targeted therapies throughout the course of management.
Recent Findings: This article reviews the recent evidence and expertise on bleeding management for haemodynamically unstable patients with pelvic fractures with insights from prehospital care to trends in resuscitation and endovascular techniques and revival of older strategies, to challenges of definitive treatment.
ACS Nano
March 2025
School of Chemical Engineering, Sichuan University, Chengdu 610065, China.
Wound-infected bacterial biofilms are protected by self-secreted extracellular polymer substances (EPS), which can confer them with formidable resistance to the host's immune responses and antibiotics, and thus delays in diagnosis and treatment can cause stubborn infections and life-threatening complications. However, tailoring an integrated theranostic platform with the capability to promptly diagnose and treat wound biofilm infection still remains a challenge. Herein, a versatile erbium-doped carbon dot-encapsulated zeolitic imidazolate framework-8 (Er:CDs@ZIF-8) nanoheterojunction (C@Z nano-HJ) is tailored and incorporated into gelatin methacrylate/poly(-hydroxyethyl acrylamide) (GelMA/PHEAA)-based tough and sticky hydrogel dressing (GH-C@Z) to achieve wound biofilm infection-integrated theranostic application.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!