Background: Currently, kidney stones are frequently observed in children and teens.
Objectives: To evaluate the safety and efficacy of mini-percutaneous nephrolithotomy (MPCNL) in managing renal stones in pediatric patients.
Patients And Methods: This retrospective case series study included 115 consecutive patients aged < 11 years old who underwent MPCNL at Sulaimani Teaching Hospital and Mercy Medical City, Sulaimaniyah, Iraq, from January 2016 to March 2021. MPCNL was done on all patients through 16-20 Fr tracts. The stone-free rate, perioperative complications, tract number, operative time, postoperative hemoglobin change, and hospitalization time were assessed.
Results: The mean patients' age was 6.53 ± 1.3 years, and the mean stone burden was 2.073 ± 1.03 cm. After a single session of MPCNL, 93.25% of patients attained a complete stone clearance through a single tract in 109 patients (94%) and two tracts in 6 patients (5.2%). Hospitalization time, operative time, postoperative hemoglobin drop, and perioperative complications were 2.23 ± 0.93 days, 39.26 ± 8.22 min, 0.51 ± 0.34 g/dL, and 25.21%, respectively. No major complications (Clavien grade III and IV) were found. Most complications were minor, including Clavien grade I (n = 18, 15.6%) and II (n = 11, 9.56%), which were managed conservatively.
Conclusions: MPCNL is an effective and potentially safe procedure for treating complex renal stones in pediatric patients aged < 11 years, yielding an excellent stone-free rate and acceptable complications.
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http://dx.doi.org/10.1186/s12882-025-04031-4 | DOI Listing |
J Microbiol Immunol Infect
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Chang Gung Microbiota Therapy Center, Chang Gung Memorial Hospital, Taoyuan, Taiwan; Molecular Infectious Disease Research Center, Chang Gung Memorial Hospital, Taoyuan, Taiwan; Division of Pediatric Infectious Diseases, Department of Pediatrics, Chang Gung Memorial Hospital, Taoyuan, Taiwan. Electronic address:
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View Article and Find Full Text PDFJ Genet Eng Biotechnol
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Department of Dermatovenereology, Kazakhstan Medical University, Almaty, Kazakhstan, 050016. Electronic address:
Astrovirus MLB1 (HAstV-MLB1) is non-enveloped RNA virus that cause acute gastroenteritis infection. Despite research progress about infection and pathogenesis of HAstV-MLB1, Currently, no vaccine has been developed to effectively combat this pathogen. The current study is based on immunoinformatics and reverse vaccinology approaches to design next-generation, multi-epitope-based vaccine models against HAstV-MLB1.
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Department of Neurology, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital.
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J Dr Nurs Pract
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Department of Nursing, Aspen University, Denver, CO, USA
At an urban public acute care hospital, a gap existed in the safety and efficacy of early mobilization (EM) of intensive care unit (ICU) patients, with the need for an evidence-based intervention. A literature review revealed that a nurse-driven mobility protocol could safely achieve early mobility in ICU patients. This quality improvement project aims to utilize a nurse-driven mobility protocol to determine its effects on EM of ICU patients.
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