A dinickel-catalyzed direct asymmetric allylic alkylation of benzocyclic ketones has been developed. This method enables the efficient transformation of various α-alkyl benzocyclohexanones and benzocyclopentanones with allylic sulfonamides, affording chiral ketones bearing α-quaternary carbon stereocenters in high yields and with excellent enantioselectivities.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/acs.orglett.5c00199 | DOI Listing |
Publication Analysis
Top Keywords
asymmetric allylic
8
allylic alkylation
8
dinickel-catalyzed asymmetric
4
allylic
4
alkylation cyclic
4
cyclic ketones
4
ketones allylic
4
allylic amine
4
amine derivatives
4
derivatives dinickel-catalyzed
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!