Human health is at risk from drinking water contamination, which causes a number of health problems in many parts of the world. The geochemistry of groundwater, its quality, the origins of groundwater pollution, and the associated health risks have all been the subject of substantial research in recent decades. In this study, groundwater in the west Rosetta Nile branch of the Nile Delta Aquifer is examined for drinking potential. Numerous water quality indices were applied, such as water quality index (WQI), synthetic pollution index (SPI) models, and health risk assessment (HRA) method. The limits of the measured parameters are used to test its drinking validity on the basis of WHO recommendations. TDS in the southern regions is within the desirable to allowable limits with percent 25.3% and 29.33%, respectively. Nearly all the study area has desirable value for HCO, Al and Ba. Ca and Mg have desirable values in the center and south portion of the investigated area, whereas in the north are unsuitable. Na, Cl and SO fall within the desired level in the regions of the south but become unsuitable towards the north. Mn and NO are inappropriate except in the northwestern part. Fe is within suitable range in the southwestern and northwestern regions. Pb, Zn, Cu, and Cd were undetected in the collected samples. Regarding to WQI the study area is classified into 4 classes good, poor, very poor and unfit for drinking water from south to north. According to SPI model, 20%, 18.7%, 18.7%, 8% and 34.6% of water samples are suitable, slightly, moderately, highly polluted and unfit, respectively from south to north. Based on HRA, Children are the most category endangered with percent 14.7% of the overall samples obtained, followed by females and males with percent 12% and 8%, respectively. This study offers insights into the conservation and management of coastal aquifers' groundwater supplies. These findings have significant implications for developing strategies and executing preventative actions to reduce water resource vulnerability and related health hazards in West Nile Delta, Egypt.
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http://dx.doi.org/10.1038/s41598-025-90477-3 | DOI Listing |
Rev Med Virol
March 2025
Department of Periodontics, University of Illinois Chicago, Chicago, Illinois, USA.
SARS-CoV-2 is an oral pathogen that infects and replicates in mucosal and salivary epithelial cells, contributing to oral post-acute sequelae COVID-19 (PASC) and other oral and non-oral pathologies. While pre-existing inflammatory oral diseases provides a conducive environment for the virus, acute infection and persistence of SARS-CoV-2 can also results in oral microbiome dysbiosis that further worsens poor oral mucosal health. Indeed, oral PASC includes periodontal diseases, dysgeusia, xerostomia, pharyngitis, oral keratoses, and pulpitis suggesting significant bacterial contributions to SARS-CoV-2 and oral tissue tropism.
View Article and Find Full Text PDFAnn Med
December 2025
Department of Psychiatry, National Clinical Research Center for Mental Disorders, and National Center for Mental Disorders, the Second Xiangya Hospital of Central South University, Changsha, Hunan, China.
Background: Despite the high prevalence of mental stress among physicians, reliable screening tools are scarce. This study aimed to evaluate the capability of the Physician Well-Being Index (PWBI) in identifying distress and adverse consequences among Chinese physicians.
Methods: This cross-sectional online survey recruited 2803 physicians from Southern Mainland China snowball sampling between October and December 2020.
Rev Environ Health
March 2025
Key Laboratory of Environment Remediation and Ecological Health, Ministry of Education, College of Natural Resources and Environmental Science, Zhejiang University, Hangzhou, China.
House dust mite (HDM) allergens are one of the most important causes of allergenic diseases in the indoor environment. The World Health Organization (WHO) has defined risk thresholds for Group I HDM allergens as a concentration of 2 and 10 μg/mL in dust for producing asthma risk and polar asthma attacks, respectively. Continuing exposure to high concentrations of HDM allergens greatly increases the risk of developing allergic diseases.
View Article and Find Full Text PDFJ Agric Food Chem
March 2025
State Key Laboratory of Agricultural Products Safety/Key Laboratory of Detection for Pesticide Residues and Control of Zhejiang, Institute of Agro-product Safety and Nutrition, Zhejiang Academy of Agricultural Sciences, Hangzhou 310021, P. R. China.
Mefentrifluconazole was the first novel isopropyl alcohol triazole fungicide. Existing research indicated that mefentrifluconazole had high activity and low toxicity, presenting potential for monocase application, while limited data existed on its enantioselective dissipation in crops. Here, after confirming the absolute configuration, the enantioselective dissipation and risk assessments of chiral mefentrifluconazole in soybeans, peanuts, tomatoes, grapes, and soil were conducted.
View Article and Find Full Text PDFSemin Diagn Pathol
March 2025
Department of Pathology, Baptist Hospital of Miami, Baptist Health System, Miami, FL, USA.
Non-invasive lobular neoplasia (LN) encompasses atypical lobular hyperplasia (ALH), classic lobular carcinoma in situ (CLCIS), florid lobular carcinoma in situ (FLCIS), and pleomorphic lobular carcinoma in situ (PLCIS). Lobular neoplasia is a neoplastic epithelial proliferation of the terminal duct lobular unit. A defining feature is discohesion due to the loss of E-cadherin, a protein that facilitates cell-to-cell adhesion.
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