To explore the mechanisms and clinical manifestations of disseminated intravascular coagulation (DIC) caused by exertional heat stroke. Analyze the clinical data of a patient with exertional heat stroke in Yichang Central People's Hospital and review relevant literature to evaluate the association between heat stroke and DIC, summarizing clinical presentations and laboratory findings. The patient exhibited symptoms such as high fever and altered consciousness after engaging in intense labor in a high-temperature environment. Laboratory tests showed a platelet count of 43×10(9)/L, D-dimer level of 5.3 mg/L, and prothrombin time of 21.8 s, which are consistent with a diagnosis of DIC. Following prompt cooling, fluid resuscitation, appropriate anticoagulant, goal-directed replacement therapy and supportive therapy, the patient's condition gradually improved. Exertional heat stroke can lead to DIC, and clinical attention should be paid to its early recognition and intervention. Effective coagulation management and timely anticoagulant and supportive therapy are crucial for improving prognosis.
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http://dx.doi.org/10.3760/cma.j.cn121090-20241225-00588 | DOI Listing |
Int J Biometeorol
March 2025
Department of Laboratory Medicine, Huanggang Central Hospital, No. 6, Qi'an Avenue, Huangzhou District, Huanggang, 438000, Hubei, China.
Stroke, a key cardiovascular disease, is impacted by cold spells and heat waves. However, limited sample size and unclear impact on the aging population's prevalence and incidence remain concerns. We aim to explore the association between cold spells and heat waves frequency and stroke in middle-aged and elderly people in China.
View Article and Find Full Text PDFJ Appl Physiol (1985)
March 2025
Computer, Electrical, and Mathematical Sciences & Engineering (CEMSE) Division, King Abdullah University of Science and Technology, Thuwal, 23955, Saudi Arabia.
Heat-related mortality remains health challenges exacerbated by climate change, with sex-based differences in outcomes, yet underlying mechanisms remain poorly understood. This study examined transcriptomic responses to heat exposure in peripheral blood mononuclear cells from 19 heat stroke patients (8 males, mean age 64.8 ± 6.
View Article and Find Full Text PDFMil Med
March 2025
Department of Psychological Science, Kennesaw State University, 1000 Chastain Road NW, Kennesaw, GA 30144, USA.
Introduction: Military service members are at risk of heat stroke, particularly due to physical exertion during training and tasks. Due to the serious nature and potentially fatal consequences of heat stroke, it is important to understand trends over time and among subgroups of service members in diagnoses of heat stroke. We aimed to replicate and extend recent work by Williams and Oh1 by examining the incidence of heat stroke in military service members from 2016 to 2021 and performing subgroup comparisons for sex, age, race, marital status, pay grade, and service branch.
View Article and Find Full Text PDFInt J Cardiol Congenit Heart Dis
March 2025
Department of Pediatric Cardiology, University Medical Center Utrecht, Utrecht, the Netherlands.
Background: Patients with transposition of the great arteries (TGA) experience reduced exercise capacity after the arterial switch operation (ASO), possibly due to limited stroke volume. This study evaluates the role of stroke volume in reduced exercise capacity in these patients.
Methods: A retrospective analysis was conducted on TGA patients who underwent a transthoracic echocardiogram (TTE), cardiac magnetic resonance (CMR) and cardiopulmonary exercise test (CPET) within one year between September 2009 and February 2024 at the University Medical Center Utrecht.
Temperature (Austin)
November 2024
School of Human Sciences (Exercise and Sports Science), The University of Western Australia, Perth, Western Australia, Australia.
Purpose: Recent field studies of physical exertion in challenging environmental conditions have reported dissociation between elevation in body core temperature (T) and successful task completion. This prompted us to further examine physiological mechanisms that might underlie variability in the response to exertional heat exposure. We hypothesized that, in response to exercise in the heat, systematic differences in central and peripheral physiological variables would be apparent between participants who successfully completed the task, versus those who became hyperthermic or symptomatic.
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