Precise percutaneous needle detection is crucial for ultrasound (US)-guided interventions. However, inherent limitations such as speckles, needle-like artifacts, and low resolution make it challenging to robustly detect needles, especially when their visibility is reduced or imperceptible. To address this challenge, we propose VibNet, a learning-based framework designed to enhance the robustness and accuracy of needle detection in US images by leveraging periodic vibration applied externally to the needle shafts. VibNet integrates neural Short-Time Fourier Transform and Hough Transform modules to achieve successive sub-goals, including motion feature extraction in the spatiotemporal space, frequency feature aggregation, and needle detection in the Hough space. Due to the periodic subtle vibration, the features are more robust in the frequency domain than in the image intensity domain, making VibNet more effective than traditional intensity-based methods. To demonstrate the effectiveness of VibNet, we conducted experiments on distinct ex vivo porcine and bovine tissue samples. The results obtained on porcine samples demonstrate that VibNet effectively detects needles even when their visibility is severely reduced, with a tip error of 1.61±1.56 mm compared to 8.15±9.98 mm for UNet and 6.63±7.58 mm for WNet, and a needle direction error of 1.64 ± 1.86° compared to 9.29 ± 15.30° for UNet and 8.54 ± 17.92° for WNet. Code: https://github.com/marslicy/VibNet.
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http://dx.doi.org/10.1109/TMI.2025.3545434 | DOI Listing |
Mikrochim Acta
March 2025
School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai, 20093, China.
A disposable, self-powered enzymatic biofuel cell (BFC) sensor integrated with a hollow microneedle array (HMNA) for glucose monitoring in interstitial fluid (ISF) is reported. The HMNA enables painless and minimally invasive ISF extraction. The BFC uses dehydrogenase (GDH) in conjunction with NAD, diaphorase (DI), and vitamin K (VK) serving as electron transfer mediators as the anode catalyst and Prussian blue (PB) as the electrochromic cathode.
View Article and Find Full Text PDFClin Cancer Res
March 2025
Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea, Seoul, Korea (South), Republic of.
Purpose: Traditional methods, fine-needle aspiration cytology (FNAC) and washout thyroglobulin (Tg), do not always provide sufficient accuracy for diagnosing lymph node (LN) metastasis in thyroid cancer. This study aimed to validate the diagnostic performance of washout cytokeratin fragment 21-1 (CYFRA 21-1) as a complementary biomarker for diagnosing metastatic LNs in thyroid cancer and to explore its relationship with molecular analysis and distant metastasis.
Patients And Methods: In this retrospective cohort study involving 230 LNs in 224 patients with PTC, FNAC, washout Tg, and CYFRA 21-1 levels were measured in suspicious LNs.
AJR Am J Roentgenol
March 2025
Department of Radiology, Duke University School of Medicine.
Architectural distortions (ADs) detected on digital breast tomosynthesis (DBT) are more frequently associated with nonmalignant pathologies than those detected on digital mammography. To evaluate outcomes of ADs detected by DBT alone with no ultrasound correlate and nonmalignant results on core needle biopsy (CNB) when adopting a management strategy selectively incorporating imaging surveillance. This retrospective study included patients with ADs detected by DBT alone with no ultrasound correlate and nonmalignant results on stereotactic CNB with 12 vacuum-assisted 9-gauge cores from July 1, 2020, to December 31, 2023.
View Article and Find Full Text PDFMater Today Bio
April 2025
Institute of Metal Research, Chinese Academy of Sciences, Shenyang, Liaoning 110016, China.
The underlying mechanisms governing the interactions between nanoparticles and vascular endothelial barrier remain largely unexplored, which is crucial for the optimal design of nanoparticles for clinical applications. In this study, the size-dependent interactions between calciprotein particles (CPPs) and endothelial cells (ECs) were investigated using a rat model of chronic kidney disease (CKD) induced by 5/6 nephrectomy. Two primary types of CPP1 were studied: small-sized CPP1 (S-CPP1, <50 nm) and larger CPP1 (L-CPP1, <100 nm), detected three and five weeks post-surgery, respectively.
View Article and Find Full Text PDFGraefes Arch Clin Exp Ophthalmol
March 2025
Department of Ophthalmology, Sisli Hamidiye Etfal Education and Research Hospital, Halaskargazi Street, 34371, Istanbul, Turkey.
Purpose: To evaluate the modified double-flanged technique in cases of subluxated foldable single-piece intraocular lenses (IOLs).
Methods: This retrospective study was conducted on 14 eyes of 14 patients.The following steps were performed in the surgical technique, respectively;the dislocated foldable single-piece IOL was repositioned into the anterior chamber, and the haptic was extracted through the corneal main incision.
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