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| http://dx.doi.org/10.1001/jamanetworkopen.2025.0008 | DOI Listing |
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Unlocking the geography of Azobé timber (Lophira alata): revealing spatial genetic structure beyond species boundaries.
BMC Plant Biol
March 2025
Forest Ecology and Forest Management, Wageningen University and Research, Wageningen, The Netherlands.
Background: The illegal trade of tropical timber constitutes a major and persistent environmental problem. Since the detection of fraud in trade documents remains challenging, forensic tools that can independently trace timber origin are needed. In this study, we evaluated the potential of the chloroplast genome (plastome) as a genetic tool to verify the claimed species and geographic origin of timber from Azobé (Lophira alata), an intensively exploited and threatened tropical tree species.
View Article and Find Full Text PDFKnowledge, attitude, and practices regarding methicillin-resistant Staphylococcus aureus (MRSA) infection control and nasal MRSA carriage rate among dental students of Al-Quds university, Palestine.
BMC Oral Health
March 2025
Department of Microbiology and Immunology, Faculty of Medicine, Al-Quds University, Jerusalem, Palestine.
Background: The nose is the primary colonization site of S. aureus which is a known risk factor for causing S. aureus infection.
View Article and Find Full Text PDFComparing conventional and Bayesian workflows for clinical outcome prediction modelling with an exemplar cohort study of severe COVID-19 infection incorporating clinical biomarker test results.
BMC Med Inform Decis Mak
March 2025
Department of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
Purpose: Assessing risk factors and creating prediction models from real-world medical data is challenging, requiring numerous modelling decisions with clinical guidance. Logistic regression is a common model for such studies, for which we advocate the use of Bayesian methods that can jointly deliver probabilistic risk factor inference and prediction. As an exemplar, we compare Bayesian logistic regression with horseshoe priors and Projective Prediction variable selection with the established frequentist LASSO approach, to predict severe COVID-19 outcomes (death or ICU admittance) from demographic and laboratory biomarker data.
View Article and Find Full Text PDFPrior authorization and utilization management for post-acute home health in Medicare Advantage: the motivations, players, processes, unique challenges, and impacts on patient care.
Health Aff Sch
March 2025
School of Public Health, Brown University, Providence, RI 02903, USA.
In 2024, 90% of Medicare Advantage (MA) enrollees were in a plan that required prior authorization of home health care. We conducted semi-structured interviews with 44 leaders of MA plans, post-acute care (PAC) management companies, and home health agencies (HHAs) across the country to understand their experiences with prior authorization and utilization management (UM) of post-acute home health care. Our analysis of these interviews revealed that representatives of MA plans and PAC management companies report varying motives and approaches to prior authorization for post-acute home health care, resulting in varied experiences for HHAs.
View Article and Find Full Text PDFSafety of iGlarLixi in Japanese People with Type 2 Diabetes: A Post-marketing Database Study.
Adv Ther
March 2025
Department of Endocrinology and Metabolism, Graduate School of Medicine, Yokohama City University, Yokohama, Japan.
Introduction: In this post-marketing study in Japan, the occurrence of hospital-treated hypoglycaemia and severe hyperglycaemia requiring inpatient treatment was evaluated in various cohorts of people with type 2 diabetes (T2D) newly switched to iGlarLixi, a titratable, once-daily, fixed-ratio combination of long-acting insulin glargine 100 U/mL (iGlar-100) and a glucagon-like peptide-1 receptor agonist (GLP-1 RA, lixisenatide).
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