Research has documented elevated experiences of racial discrimination among African American families, and its adverse impacts on their psychological well-being. However, most studies have investigated the experiences of and consequences for older children and adults. The goal of the current study was to examine the relations among mothers' perception of discrimination during pregnancy, pre- and post-natal depressive symptoms, and infant development in African American families from low-income backgrounds. Using a longitudinal design with questionnaires and direct assessments, this study included 118 African American mothers (and infants) who participated in three data collection sessions: the third trimester of pregnancy (home); 4 weeks postpartum (phone); and when infants were 4-6 months old (home). Analyses revealed that mothers' perceived prenatal discrimination was strongly associated with depressive symptomatology and that maternal depression was related to infant cognitive and fine motor skills. Perceived prenatal discrimination was significantly related to infant cognitive development. For mothers with higher levels of perceived discrimination, a higher level of depressive symptomatology was related to receptive language. These findings are considered in the context of the extant literature on perinatal stress, maternal functioning, and young infant outcomes. Implications for early childhood and infant mental health practice are discussed.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1002/imhj.70010 | DOI Listing |
Nat Med
March 2025
Renal Division, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
African American (AA) kidney transplant recipients exhibit a higher rate of graft loss compared with other racial and ethnic populations, highlighting the need to identify causative factors. Here, in the Genomics of Chronic Allograft Rejection cohort, pretransplant blood RNA sequencing revealed a cluster of four consecutive missense single-nucelotide polymorphisms (SNPs), within the leukocyte immunoglobulin-like receptor B3 (LILRB3) gene, strongly associated with death-censored graft loss. This SNP cluster (named LILRB3-4SNPs) encodes missense mutations at amino acids 617-618 proximal to a SHP1/2 phosphatase-binding immunoreceptor tyrosine-based inhibitory motif.
View Article and Find Full Text PDFTransplantation
March 2025
Scientific Registry of Transplant Recipients (SRTR), Minneapolis, MN.
Background: Kidney transplant offers better outcomes and reduced costs compared with chronic dialysis. However, racial and ethnic disparities in access to kidney transplant persist despite efforts to expand access to transplant and improve the equity of deceased donor allocation. Our objective was to evaluate after listing the association of race and ethnicity with access to deceased donor kidney transplant (DDKT) after changes to the allocation system in 2014.
View Article and Find Full Text PDFClin Lung Cancer
February 2025
Henry Ford Cancer Center, Detroit, MI.
Background: EGFR alterations have significant therapeutic implications in lung cancer (LCa), yet their prevalence and co-mutational patterns in African American populations remain understudied. This study analyzes EGFR-mutant LCa across races using the Tempus database.
Methods: De-identified records sequenced via Tempus xT assay, (595 to 648 gene DNA panel) were included if they had ≥ 1 pathogenic EGFR mutation (short variants (SVs), copy number amplifications (CNAs), or fusions).
AIDS Care
March 2025
Department of Behavioral and Social Sciences, Brown University School of Public Health, Providence, RI, USA.
Social norms, particularly those pertaining to gender equity, can shape attitudes and behaviors that contribute to adolescent sexual violence (SV). This study examines personal attitudes and perceived peer norms regarding gender equity and associations with perpetration of SV among 100 South Africans aged 13-17 in 2019. We assessed: (1) sexual activity and SV behaviors and (2) personal attitudes and perceived peer norms around gender equity.
View Article and Find Full Text PDFPLoS Negl Trop Dis
March 2025
School of Life Sciences, University of Warwick, Warwick, United Kingdom.
Leishmaniasis affects military personnel deployed to endemic areas following exposure to sand flies infected with the protozoa Leishmania. This systematic review and meta-analysis of data specific to military populations aims to identify knowledge gaps to mitigate sand fly exposure and Leishmania transmission during deployments. The review was registered on PROSPERO (CRD42023463687).
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!