Setting: TB screening cascade and performance of active case-finding strategies across six states of Nigeria.
Objective: To analyse the impact of portable digital X-ray (PDX) on TB screening in hard-to-reach areas in Nigeria.
Design: A cross-sectional study involving enrollees with a CAD4TB score of ≥50 had Xpert (sputum) and/or radiographic assessment for TB diagnosis. A TB screening algorithm guided the step-by-step process of identifying a presumptive TB client up to diagnosis and linkage for appropriate treatment. Data were collected, collated, and reported using the national TB tools.
Results: Seven PDX with CAD4TB used as TB screening and diagnostic tools across six states screened 85,910 persons and identified 8,416 presumptive TB cases. From this study, PDX had the lowest number needed to screen (NNS) of 45 and the number needed to test (NNT) of 4. Similarly, PDX, with a presumptive TB yield of 10%, had the highest TB yield of 23%.
Conclusion: Using PDX with CAD contributed to the highest TB yield during Active TB case finding in hard-to-communities of Nigeria. With a very low NNS and NNT, its national scale-up and use across remote locations will significantly improve TB case-finding.
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http://dx.doi.org/10.5588/pha.24.0040 | DOI Listing |
Appl Med Artif Intell (2024)
February 2025
Center for Advanced Medical Computing and Analysis, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114, USA.
Head motion is a major source of image artifacts in head computed tomography (CT), degrading the image quality and impacting diagnosis. Image-domain-based motion correction is practical for routine use since it doesn't rely on hard-to-obtain CT projection data. However, existing convolutional neural network (CNN)-based methods tend to over-smooth images, particularly in cases of moderate to severe 3D motion artifacts.
View Article and Find Full Text PDFHealthcare (Basel)
March 2025
Research Group in Nursing and Health Care, Puerta de Hierro Health Research Institute-Segovia de Arana (IDIPHISA), 28222 Majadahonda, Spain.
Background: Joint manipulation is commonly used to manage musculoskeletal dysfunctions. Joint manipulation can result in audible sounds. The clinical significance and cause of manipulation sound remain unclear.
View Article and Find Full Text PDFJ Phys Condens Matter
March 2025
Zhengzhou University, kexue dadao No.100,zhengzhou, Zhengzhou, 450001, CHINA.
The depletion of fossil fuels and the environmental impact of chemical batteries, coupled with the rapid proliferation of portable electronic devices and the Internet of Things (IoT), have created an urgent demand for high-performance, lightweight, and sustainable energy systems. Flexible triboelectric nanogenerators (TENGs) have emerged as a promising technology for powering self-sufficient devices, offering advantages such as simple structure, flexibility, low cost, and environmental adaptability. In particular, electrospun nanofiber-based TENGs stand out due to their enhanced surface area, superior charge collection capabilities, and improved mechanical durability.
View Article and Find Full Text PDFPain Ther
March 2025
Unit of Internal Medicine, Fondazione Policlinico Universitario Campus Bio-Medico, Via Alvaro del Portillo, 200, 00128, Rome, Italy.
Introduction: Opioid-induced constipation (OIC) is a common side effect of chronic opioid therapy that significantly impacts quality of life and healthcare costs. Naldemedine, a peripherally acting mu-opioid receptor antagonist, has shown efficacy in treating OIC. However, real-world evidence on naldemedine use in the United States is limited, particularly in older adults.
View Article and Find Full Text PDFDela J Public Health
December 2024
Department of Family Medicine, Warren Alpert Medical School at Brown University.
Objective: To investigate if a telehealth option as the initial postpartum visit would increase postpartum visit attendance.
Methods: This was a retrospective cohort study of women receiving prenatal care through a federally qualified health center, Westside Family Health in Delaware, comparing attendance at a postpartum visit before telehealth was an option (2018) versus after the onset of the pandemic (2021). Representative random samples were taken from one year of deliveries pre- and post-implementation of the telehealth visit option.
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