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| http://dx.doi.org/10.1016/j.opresp.2025.100405 | DOI Listing |
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Impact of Different Mediastinal Staging Modalities on Target Volume Delineation in Locally Advanced Non-Small-Cell Lung Cancer: A Secondary Analysis of the Multicenter Randomized PET-Plan Trial.
Int J Radiat Oncol Biol Phys
March 2025
Department of Radiation Oncology, Faculty of Medicine, University Medical Center Freiburg, University of Freiburg, Freiburg, Germany; Department of Radiation Oncology, University Hospital Bonn, Bonn, Germany. Electronic address:
Purpose: To evaluate the role of different invasive and non-invasive mediastinal staging methods in patients with locally advanced non-small-cell lung cancer (NSCLC) treated with definitive chemoradiotherapy in the prospective XXX trial (XXX; NCTXXX) and to evaluate the impact of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) and mediastinoscopy on target volume definition.
Methods: Patients treated per-protocol (n = 172), all receiving isotoxically dose-escalated chemoradiotherapy, were included in this unplanned secondary analysis. Radiation treatment planning was based on an F-FDG PET/CT targeting all CT positive lymph nodes (i.
Tracheal nodularity and paratracheal soft tissue nodule: post-radioactive iodine treatment changes with peculiar visual and pathologic findings in a case of metastatic follicular variant papillary thyroid carcinoma: a case report.
J Med Case Rep
March 2025
Interventional Pulmonology, Department of Medicine, University of California San Diego, La Jolla, CA, 92037, USA.
Background: Follicular variant papillary thyroid carcinoma is a distinct subtype of papillary thyroid carcinoma that can occasionally present with aggressive features, including distant metastases and extrathyroidal extension. While radioactive iodine ablation is a well-established treatment for residual disease, its post-treatment effects on tracheal and paratracheal structures remain poorly characterized.
Case Presentation: A 22-year-old male individual of Taiwanese descent presented with an enlarged neck mass and was diagnosed with follicular variant papillary thyroid carcinoma.
Prediction of Lymph Node Metastasis in Lung Cancer Using Deep Learning of Endobronchial Ultrasound Images With Size on CT and PET-CT Findings.
Respirology
March 2025
Division of Pulmonology, Center for Lung Cancer, National Cancer Center, Goyang, Korea.
Background And Objective: Echo features of lymph nodes (LNs) influence target selection during endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA). This study evaluates deep learning's diagnostic capabilities on EBUS images for detecting mediastinal LN metastasis in lung cancer, emphasising the added value of integrating a region of interest (ROI), LN size on CT, and PET-CT findings.
Methods: We analysed 2901 EBUS images from 2055 mediastinal LN stations in 1454 lung cancer patients.
Cytologic Diagnoses of Lung Adenocarcinoma With Concomitant Metastasis From a Different Primary: A Case Series.
Diagn Cytopathol
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University of Virginia School of Medicine Inova Campus, Falls Church, Virginia, USA.
Lung adenocarcinoma is a common malignancy that can metastasize. The lung is also a common site for metastasis from other sites. Prompt and accurate diagnosis is critical for patient management.
View Article and Find Full Text PDFEndobronchial Ultrasound-Guided Transbronchial Mediastinal Cryobiopsy: Tunneling With Different Needle Gauges.
Open Respir Arch
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Department of Pathology, Hospital Universitario Rio Hortega, Valladolid, Spain.
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