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| http://dx.doi.org/10.4103/heartviews.heartviews_81_24 | DOI Listing |
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Department of Pediatrics, Division of Pediatric Cardiology, Medical College of Wisconsin, Milwaukee (T.B., J.R.K., A.J.K., J.L.).
Background: Heart valve function requires a highly organized ECM (extracellular matrix) network that provides the necessary biomechanical properties needed to withstand pressure changes during each cardiac cycle. Lay down of the valve ECM begins during embryogenesis and continues throughout postnatal stages when it is remodeled into stratified layers and arranged according to blood flow. Alterations in this process can lead to dysfunction and, if left untreated, heart failure.
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Seymour, Paul and Gloria Milstein Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center and NewYork-Presbyterian Hospital (Y.A.C., M.S., M.C., L.L.J., A.J.E.).
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View Article and Find Full Text PDFLow-level neurostimulation of the renal nerves as a potential therapeutic strategy for hypertension treatment.
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