This work presents an enhanced identification procedure utilising bioinformatics data, employing optimisation techniques to tackle crucial difficulties in healthcare operations. A system model is designed to tackle essential difficulties by analysing major contributions, including risk factors, data integration and interpretation, error rates and data wastage and gain. Furthermore, all essential aspects are integrated with deep learning optimisation, encompassing data normalisation and hybrid learning methodologies to efficiently manage large-scale data, resulting in personalised healthcare solutions. The implementation of the suggested technology in real time addresses the significant disparity between data-driven and healthcare applications, hence facilitating the seamless integration of genetic insights. The contributions are illustrated in real time, and the results are presented through simulation experiments encompassing 4 scenarios and 2 case studies. Consequently, the comparison research reveals that the efficacy of bioinformatics for enhancing routes stands at 7%, while complexity diminish to 1%, thereby indicating that healthcare operations can be transformed by computational biology.
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http://dx.doi.org/10.1177/11795972251321684 | DOI Listing |
JMIR Form Res
March 2025
Program in Digital Medicine, Department of Medicine, University of Massachusetts Chan Medical School, Worcester, MA, United States.
Background: Screening for cognitive impairment in primary care is important, yet primary care physicians (PCPs) report conducting routine cognitive assessments for less than half of patients older than 60 years of age. Linus Health's Core Cognitive Evaluation (CCE), a tablet-based digital cognitive assessment, has been used for the detection of cognitive impairment, but its application in primary care is not yet studied.
Objective: This study aimed to explore the integration of CCE implementation in a primary care setting.
JMIR Res Protoc
March 2025
Paseo de los Encomendadores, Faculty of Health Sciences, University of Burgos, Burgos, Spain.
Background: Breast cancer is the second most common cancer in women worldwide. Treatments for this disease often result in side effects such as pain, fatigue, loss of muscle mass, and reduced quality of life. Physical exercise has been shown to effectively mitigate these side effects and improve the quality of life in patients with breast cancer.
View Article and Find Full Text PDFJMIR Res Protoc
March 2025
Institute for Data Science and Informatics, University of Missouri, Columbia, MO, United States.
Background: Amyotrophic lateral sclerosis (ALS) leads to rapid physiological and functional decline before causing untimely death. Current best-practice approaches to interdisciplinary care are unable to provide adequate monitoring of patients' health. Passive in-home sensor systems enable 24×7 health monitoring.
View Article and Find Full Text PDFPediatr Infect Dis J
March 2025
Department of Paediatrics and Child Health, Stellenbosch University and Tygerberg Hospital, Cape Town, South Africa.
Background: Children living with HIV are at higher risk for hearing loss compared to children with HIV-unexposed, uninfected (HUU). There is little known regarding the effects of children living with perinatally-acquired HIV (PHIV) and those living with perinatal HIV exposure but uninfected (PHEU) on central auditory function.
Methods: Children aged 11-14 years who were participating in the Auditory Research in Children with HIV study.
J Infect Dis
March 2025
Service de Médecine Intensive Réanimation, Hôpitaux Universitaires Henri Mondor - Albert Chenevier, Assistance Publique-Hôpitaux de Paris (AP-HP), 94010 Créteil, France.
Background: Respiratory syncytial virus (RSV) is one of the deadliest respiratory viruses. There is a need to better identify prognostic factors in RSV-infected patients, particularly those requiring intensive care unit (ICU) admission, with a focus on immunosuppressed patients.
Methods: Multicenter, retrospective cohort study of RSV-infected adults hospitalized in 17 ICUs in the Great Paris area between 08/01/2017 and 05/01/2023.
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