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| http://dx.doi.org/10.1017/ash.2025.30 | DOI Listing |
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The Drug Allergy History Tool (DAHT): Validation of a Patient-Reported Survey Instrument.
J Allergy Clin Immunol
March 2025
Division of Allergy and Immunology, Department of Medicine, University of Texas Southwestern Medical Center, Dallas, TX.
Background: While the reaction history is critical for drug allergy evaluations and is typically self-reported, there is no validated survey instrument to collect drug allergy history from patients.
Objective: To validate a survey instrument that collects patient-reported drug allergy history.
Methods: The Drug Allergy History Tool (DAHT) was revised after three rounds of cognitive testing, with data assessed for reliability, through test-retest comparison, and quality and validity, through a concordance analysis against electronic health record (EHR) allergist documentation.
Labeling barriers to delabeling penicillin allergy: an intersectional case study of gender identity, race, and syphilis.
J Allergy Clin Immunol Pract
March 2025
Section of Rheumatology, Allergy and Immunology, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT. Electronic address:
Vonoprazan improves the efficacy of bismuth quadruple therapy containing doxycycline and metronidazole as first-line Helicobacter pylori treatment in penicillin-allergic patients: a randomized controlled trial.
J Antimicrob Chemother
March 2025
Department of Gastroenterology, Zhejiang Provincial Clinical Research Center for Digestive Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.
Background: Helicobacter pylori eradication in penicillin-allergic patients presents challenges. Options of effective regimens are lacking in areas where tetracycline is unavailable.
Objectives: To evaluate the efficacy of replacing the proton pump inhibitor (PPI) with a potassium-competitive acid blocker (P-CAB, vonoprazan) in standard bismuth quadruple therapy containing doxycycline and metronidazole as a first-line treatment for H.
National expert consensus on the management of antibiotic prophylaxis in surgical patients with a penicillin allergy label based on the Delphi method.
JAC Antimicrob Resist
April 2025
Paris Cité University, Paris, France.
Background: Patients with a penicillin allergy label have an increased risk of surgical site infection. Although a decision tree was published in 2019 to define which patients could benefit from direct cephalosporin use in the perioperative setting, this strategy remains unvalidated. This consensus statement aimed to adapt it based on an expert consensus to cover persisting caveats and to adapt it to an environment with poor allergist resources.
View Article and Find Full Text PDFPenicillin allergy delabeling in long-term care facilities: if not now, then when?
Antimicrob Steward Healthc Epidemiol
February 2025
Section of Infectious Diseases, Boston Medical Center, Boston, MA, USA.
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