The magnetic traits of sonochemically synthesized CoNiInSeFeO nanoparticles [(In/Se → CoNiFeO) ( ≤ 0.1) NPs] have been investigated in detail. X-ray powder diffraction analysis confirmed the purity and cubic phase crystalline structure of all products. The products' chemical composition has been confirmed by EDX and elemental mapping analyses. The magnetization characteristics of CoNiInSeFeO (In/Se → CoNiFeO) ( ≤ 0.1) NPs revealed superparamagnetic behavior at room temperature and ferrimagnetic behavior at low temperatures (). The blocking temperature () that defines the superparamagnetic-ferrimagnetic state transition was also determined via analysis of the ZFC and FC magnetization curves. was found to move to lower as the amount of selenium amount increased. Moreover, the undoped CoNiFeO NPs displayed the highest magnetic characteristics (such as , , , , and ), which are depressed after In/Se codoping. The superparamagnetic feature could be promising for some interesting applications, including biosensing, magnetic hyperthermia, magnetic resonance imaging, and targeted drug delivery, while the ferrimagnetic behavior can make the material interesting for electrical applications.
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http://dx.doi.org/10.1021/acs.inorgchem.5c00276 | DOI Listing |
Immune Netw
February 2025
Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul 03080, Korea.
Aromatic amino acid (AAA) metabolites, derived from tryptophan, phenylalanine, and tyrosine through coordinated host and microbial metabolism, have emerged as critical modulators of immune function. We examine the complex journey of AAAs from dietary intake through intestinal absorption and metabolic transformation, highlighting the crucial role of host-microbe metabolic networks in generating diverse immunomodulatory compounds. This review provides a unique integrative perspective by mapping the molecular mechanisms through which these metabolites orchestrate immune responses.
View Article and Find Full Text PDFSci Rep
March 2025
Department of Cardiology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200030, China.
Although the pathogenesis of abdominal aortic aneurysm (AAA) remains largely unclear, evidence is accumulating to suggest the systemic nature of this disease. Here, we comprehensively assessed the whole aortic tree with its major branches based on computed tomography angiography (CTA) in AAA patients compared to ascending thoracic aortic aneurysm (ATAA) patients and nonaneurysmal controls, as well as in an original mouse model of AAA in Lkb1;Myh11-Cre/ERT2 mice. The morphology and dimensions of the whole aorta (at different levels) and its major branches were compared among 47 AAA patients, 47 ATAA patients, and 46 nonaneurysmal controls based on CTA images.
View Article and Find Full Text PDFEndocr Pathol
March 2025
Division of Oncology, Department of Medicine I, Medical University of Vienna, Vienna, Austria.
Neuroendocrine tumors (NET) of the lung constitute a rare entity of primary lung malignancies that often exhibit an indolent clinical course. Epigenetics-related differences have been described previously for lung NET, but the clinical significance remains unclear. In this study, we performed genome-wide methylation analysis using the Infinium MethylationEPIC BeadChip technology on FFPE tissues from lung NET treated at two academic centers.
View Article and Find Full Text PDFClin Sci (Lond)
March 2025
Universidad Rey Juan Carlos Facultad de Ciencias de la Salud, Alcorcón, Spain.
Endoplasmic reticulum (ER) stress plays a critical role in the abdominal aortic aneurysm (AAA), a life-threatening disease characterized by inflammation, destructive remodeling and vascular smooth muscle cells (VSMC) dysfunction. The current therapy relies on surgical repair, but no effective pharmacological strategies are available to limit aneurysm progression. LncRNAs are essential factors in health and disease, however, their specific contribution to AAA development and its relationship with ER stress remains unexplored.
View Article and Find Full Text PDFJ Pharm Bioallied Sci
December 2024
Department of Oral Medicine and Radiology, Kalinga Institute of Dental Sciences, KIIT Deemed to be University, Bhubaneswar, Odisha, India.
Introduction: This study compares the efficacy of orthopantomography (OPG), conebeam computed tomography (CBCT), and magnetic resonance imaging (MRI) in diagnosing the alveolar antral artery (AAA) within the maxillary sinus.
Materials And Methods: Conducted among 297 patients in Odisha, with ages ranging from 20 to 50 years, the study utilized three observers to ensure reliability. Results indicated that MRI is the gold standard for AAA visualization, with high intraand interobserver reliability (Cohen's kappa = 1.
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