Objective: Aim: To assess the effects of honey and its derivatives on oral health.
Patients And Methods: Materials and methods: PubMed, Google Scholar, Scopus, Embase, Cochrane databases were searched using relevant keywords and Boolean operators.
Conclusion: Conclusions: Honey is a promising natural alternative for the treatment of various dental diseases due to its antimicrobial, anti-inflammatory and wound-healing properties. Scientific studies show that honey has numerous health properties, including antibacterial, antiviral, anti-inflammatory, wound-healing and anticancer effects. In the context of dentistry, honey shows potential in the treatment of various oral conditions, such as dental caries, gingivitis, halitosis, radiotherapy-induced mucositis, xerostomia or post-extraction stomatitis. Honey's safety and multifunctional benefits make it a valuable potential addition to dental treatments.
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http://dx.doi.org/10.36740/WLek/199734 | DOI Listing |
Clin Cosmet Investig Dermatol
March 2025
Beijing Uproven Medical Technology Co., LTD., Beijing, People's Republic of China.
This review article explores the potential applications of chitosan, a natural polysaccharide derived from crustacean shells, in the treatment of seborrheic dermatitis (SD) and other skin diseases. SD is a common chronic inflammatory skin condition characterized by erythema, scaling, itching, and an oily appearance, predominantly affecting areas rich in sebaceous glands. Current treatments, including antifungal agents, corticosteroids, and calcineurin inhibitors, offer symptomatic relief but have limitations in long-term use due to side effects and resistance issues.
View Article and Find Full Text PDFActa Biomater
March 2025
Department of Chemistry in Pharmaceutical Sciences, School of Pharmacy, Institute Hospital 12 de Octubre (imas12), Universidad Complutense de Madrid (UCM), 28040, Spain; Networking Research Center on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Madrid 28029, Spain. Electronic address:
In the present era, the treatment of skin-infected wounds and their associated inflammation constitutes a significant challenge. These infections have the potential to impede the healing process and become a life-threatening pathology, particularly due to the rise of bacterial resistance. Hydrogels could successfully address this issue due to their unique capabilities and versatility.
View Article and Find Full Text PDFBiomed Pharmacother
March 2025
Department and Institute of Pharmacology, School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan; Cardiovascular Research Center, Taipei Medical University Hospital, Taipei, Taiwan; Ph.D. Program of Interdisciplinary Medicine and Biomedical Industry, National Yang Ming Chiao Tung University, Taipei, Taiwan. Electronic address:
The accumulation of uremic toxins in circulation contributes to the cardiovascular diseases that result from chronic kidney disease (CKD). Indoxyl sulfate (IS), which is a protein-bound uremic toxin, promotes cardiovascular diseases with impaired neovascularization by increasing the reactive oxygen species (ROS). This study aimed to investigate febuxostat, a potent xanthine oxidase (XO) inhibitor, for its potential effects on the mechanisms of neovasculogenesis in CKD.
View Article and Find Full Text PDFBurns Trauma
March 2025
Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, No. 6 West Xuefu Road, Xinpu New District, Zunyi 563006, China.
Background: Diabetic wounds pose significant clinical challenges due to impaired healing processes, often resulting in chronic, nonhealing ulcers. Asiaticoside (AC), a natural triterpene derivative from , has demonstrated notable anti-inflammatory and wound-healing properties. However, the synergistic effects of nitric oxide (NO)-a recognized promoter of wound healing-combined with AC in treating diabetic wounds remain inadequately explored.
View Article and Find Full Text PDFJ Neuroinflammation
March 2025
Neuroscience Program, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.
Spinal cord injury (SCI) can cause permanent dysfunction proceeding from multifaceted neuroinflammatory processes that contribute to damage and repair. Fidgetin-like 2 (FL2), a microtubule-severing enzyme that negatively regulates axon growth, microglial functions, and wound healing, has emerged as a potential therapeutic target for central nervous system injuries and neuroinflammation. To test the hypothesis that FL2 knockdown increases acute neuroinflammation and improves recovery after SCI, we examined the effects of nanoparticle-encapsulated FL2 siRNA treatment after a moderate contusion SCI in rats.
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