Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.vetmic.2025.110447 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
The mechanisms of resistance, epidemiological characteristics, and molecular evolution of carbapenem-resistant hypervirulent Klebsiella pneumoniae.
Lab Med
March 2025
Department of Clinical Laboratory, People's Hospital of Dayi County, Chengdu Sichuan, China.
Introduction: Carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKP) is a highly pathogenic, drug-resistant, and transmissible "superbug" that causes infections in hospitals and communities. Because of the lack of effective antimicrobial treatment options, morbidity and mortality from CR-hvKP infections have increased dramatically, and outbreaks and the rapid spread of CR-hvKP in hospitals have become a major global public health challenge.
Methods: The mechanisms of molecular evolution in CR-hvKP include the acquisition of a hypervirulent plasmid encoding a virulence gene by carbapenemase-producing K pneumoniae, the horizontal transfer of plasmids carrying carbapenem resistance genes to hvKP, and the acquisition of fusion plasmids carrying both carbapenem resistance genes and hypervirulent genes by classic K pneumoniae.
Isolation and Functional Characterization of Endophytic Bacteria from Muscadine Grape Berries: A Microbial Treasure Trove.
Cells
March 2025
Center for Viticulture & Small Fruit Research, Florida A&M University, Tallahassee, FL 32317, USA.
Muscadine grapes are renowned for their unique traits, natural disease resistance, and rich bioactive compounds. Despite extensive research on their phytochemical properties, microbial communities, particularly endophytic bacteria, remain largely unexplored. These bacteria play crucial roles in plant health, stress tolerance, and ecological interactions.
View Article and Find Full Text PDFMesenchymal stem/stromal cells (MSCs) offer promising therapeutic potential in cell-based therapies for various diseases. However, the safety of genetically modified MSCs remains poorly understood. This study aimed to evaluate the general toxicity and safety of Wharton's Jelly-Derived MSCs (WJ-MSCs) engineered to express the antimicrobial peptide SE-33 in an animal model.
View Article and Find Full Text PDFRevealing the clinical relevance of .
Microbiol Spectr
March 2025
Department of Microbiology and Infection Control, University Hospital of North Norway, Tromsø, Norway.
Unlabelled: , previously misidentified as , was first described as a new species in 2020. In this study, we aimed to describe the clinical relevance of by combining clinical data, antibiotic susceptibility profiles, and biofilm formation in isolates obtained from hospitalized and non-hospitalized patients. We established a collection of 129 .
View Article and Find Full Text PDFThe impact of anthropogenic activities on antimicrobial and heavy metal resistance in aquatic environments.
Appl Environ Microbiol
March 2025
School of Environmental and Life Sciences, The University of Newcastle, Callaghan, New South Wales, Australia.
Unlabelled: This study investigated the prevalence and co-occurrence of antimicrobial (AMR) and metal resistance (MR) in aquatic environments with different human impacts. Metagenomes from pristine, rural and urban sites in Australia were analyzed with AMR ++ and customized binning pipelines. AMR was present in all environments, while MR was mainly in rural and urban samples.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!