Background: Tuberculosis mostly affects adults in their most productive years. However, all age groups are at risk. One of the high risk groups for tuberculosis is the elderly population due to factors like physiological ageing related changes, presence of comorbidities and immunodeficiency.
Objective: 1. To estimate the prevalence of pulmonary tuberculosis among the elderly population residing in selected old age homes.2. To assess the epidemiological profile of pulmonary tuberculosis among the elderly population residing in selected old age homes.
Methodology: An analytical cross sectional study was carried out among elderly inmates (N - 300) of selected 10 old age homes in Salem district of Tamilnadu. A pre tested semi-structured questionnaire was used as a study tool for data collection. Investigations like CBNAAT and X ray were carried out on individuals with presumptive symptoms.
Results: Among 300 participants, about 50.7% were between 61 and 70 Years and 60.7% were females. Nearly 4.3% were current smokers, 28.7% were hypertensive and 20.6% were diabetic About 15.6% had cough, 11.2% had fever and 4.8% had hemoptysis Prevalence of tuberculosis was 2.6% (260 per 10,000 popultion) in this study. Tuberculosis was reported more in Females, those with presumptive symptoms, underweight individuals, those living in dormitory and those with comorbidity.
Conclusion: The results indicate that the key population should be concentrated for routine screening for tuberculosis. Pro-active interventions to seek and diagnose TB disease among older adults are more effective than traditional passive case-finding as we march towards elimination of tuberculosis in India.
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http://dx.doi.org/10.1016/j.ijtb.2024.08.019 | DOI Listing |
Background: Differential diagnosis of pleural effusions poses a considerable challenge in clinical practice. In this study, we explored biomarkers in pleural fluid for distinguishing tuberculosis, malignant, and parapneumonic pleural effusion patients.
Methods: A total of 166 patients with exudative pleural effusion were collected, including 86 patients with tuberculosis pleural effusion (TPE), 52 patients with malignant pleural effusion (MPE), and 28 patients with parapneumonic effusion (PE).
Background: Tuberculosis is still a significant global health challenge, with latent tuberculosis infection (LTBI) posing a risk for the development of active disease. This study aimed to compare the performance of the STAN-DARD F TB-Feron FIA test with the QuantiFERON-TB Gold Plus, a test endorsed by the World Health Organization (WHO), in detecting LTBI.
Methods: We included 137 participants, out of which 58.
Int J Gen Med
March 2025
Department of Clinical Laboratory, Infectious Disease Hospital of Heilongjiang Province, Harbin City, Heilongjiang Province, 150500, People's Republic of China.
Objective: The aim of this study was to evaluate lymphocyte subsets and clinical outcomes in patients with pulmonary tuberculosis (PTB) combined with type 2 diabetes mellitus (T2DM).
Methods: Between January 2022 and March 2024, 320 patients aged > 60 years were included, 95 of whom had comorbid DM. Lymphocyte subsets (T-lymphocytes, B-lymphocytes, and natural killer cells, NK) were assessed in both groups of patients using fluorescence-associated cell sorting.
Virol J
March 2025
Department of Information, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Background: Human papillomavirus (HPV) infection is a key factor in the development of cervical cancer and HPV genotyping is crucial for screening. There are significant differences in the pathogenic potential of the various HPV types. Currently, clinical data on HPV82 are scarce, and the relationship between its viral load, pathogenicity, and persistence is unknown.
View Article and Find Full Text PDFBMC Health Serv Res
March 2025
Asian Institute for Bioethics and Health Law, College of Medicine, Yonsei University, Seoul, Korea.
Introduction: The COVID-19 burden, coupled with unprecedented control measures including physical distancing, travel bans, and lockdowns in cities, has undoubtedly far-reaching consequences on healthcare services and has affected human immunodeficiency virus (HIV) and tuberculosis (TB) health services in both low- and high-income countries. This study, therefore, explored the perspective of HIV and TB health service providers to better understand how the pandemic impacted health service delivery in Ghana.
Method: This qualitative explorative study was conducted among HIV and TB healthcare providers (n = 30) in six districts of Ghana from March to May 2021 using in-depth interviews.
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