Background: Pain management in posterior fossa surgeries poses significant challenges, with opioid-based approaches causing unwanted side effects. This study evaluates the efficacy of posterior scalp block using bupivacaine and dexmedetomidine compared to skin infiltration for managing perioperative pain.
Methods: In this prospective, double-blind, randomized controlled trial, 34 adult patients undergoing elective posterior fossa surgeries were equally assigned to either posterior scalp block or skin infiltration groups. Outcomes measured included hemodynamic parameters, pain scores, opioid consumption, time to first analgesic, and sedation levels.
Results: The posterior scalp block group showed significantly lower opioid consumption (211.47 ± 101.95 mcg vs 305.88 ± 117.10 mcg; < 0.01) and pain scores (VAS 2.29 ± 0.9 vs 5.06 ± 1.3; < 0.001) at 24 hours post-surgery. This group also demonstrated better hemodynamic stability and fewer rescue opioid requirements (9 vs 15 patients; < 0.009).
Conclusions: Posterior scalp block with bupivacaine and dexmedetomidine significantly improves pain management, reduces opioid use, and provides better hemodynamic stability compared to skin infiltration in posterior fossa surgeries.
Clinical Trial Registration: CTRI/2023/07/0554959.
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http://dx.doi.org/10.1080/17581869.2025.2470607 | DOI Listing |
Epilepsy Behav Rep
March 2025
Department of Stroke, Institute of Medicine, University of Tsukuba, 1-1-1, Tennodai, Tsukuba, Ibaraki 305-8575, Japan.
Identifying epileptogenic zones non-invasively is challenging due to signal interference by the scalp and skull, necessitating invasive methods like subdural recordings and stereoelectroencephalography. Recent microcatheter advancements suggest that a microcatheter-compatible endovascular EEG (eEEG) device could overcome these barriers. We developed a thin, flexible eEEG electrode, the EP-01, for use with current microcatheters.
View Article and Find Full Text PDFPain Manag
March 2025
Department of Anaesthesiology, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, India.
Background: Pain management in posterior fossa surgeries poses significant challenges, with opioid-based approaches causing unwanted side effects. This study evaluates the efficacy of posterior scalp block using bupivacaine and dexmedetomidine compared to skin infiltration for managing perioperative pain.
Methods: In this prospective, double-blind, randomized controlled trial, 34 adult patients undergoing elective posterior fossa surgeries were equally assigned to either posterior scalp block or skin infiltration groups.
Brain Stimul
February 2025
Department of Human Neurophysiology, Institute of Brain Medical Sciences, Fukushima Medical University, Fukushima, Japan.
Background: Motor responses evoked by transcranial magnetic stimulation (TMS) using posterior-anterior (PA) and anterior-posterior (AP) current directions have distinct latencies and thresholds. However, the underlying reasons for these differences remain unclear.
Objective: To quantify the differences in activation sites between PA- and AP-TMS.
J Neurosurg Case Lessons
February 2025
Department of Neurological Surgery, Renaissance School of Medicine at Stony Brook University, Stony Brook, New York.
Background: Chiari malformations type I are commonly encountered in pediatric patients. Posterior fossa decompression with or without duraplasty is recommended for patients with intractable symptoms, as well as those showing evidence of brainstem dysfunction.
Observations: In this report, the authors describe the case of a 19-year-old female who presented to the neurosurgery clinic with delayed synthetic dural graft breakdown as well as associated pseudomeningocele and intracranial hypotension.
Cureus
January 2025
Oncology, East Alabama Medical Center, Opelika, USA.
The clinical progression of metastatic breast cancer may be indicated by dermatologic manifestations of the internal malignancy. Although uncommon, underlying malignancies can metastasize to the scalp and resemble various common dermatological lesions. We report the case of a 62-year-old female patient with a history of mammary ductal carcinoma who presented with a metastatic papule on the posterior mid-parietal scalp.
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