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Eight Days a Week - BALANCING Duration and Efficacy.
N Engl J Med
March 2025
Division of Infectious Diseases, Department of Medicine, Duke University Medical Center, Durham, NC.
The Case for Preregistering Quasi-Experimental Program and Policy Evaluations.
Eval Rev
March 2025
Graduate School of Education, Stanford University, Stanford, CA, USA.
The recognition that researcher discretion coupled with unconscious biases and motivated reasoning sometimes leads to false findings ("p-hacking") led to the broad embrace of study preregistration and other open-science practices in experimental research. Paradoxically, the preregistration of quasi-experimental studies remains uncommon although such studies involve far more discretionary decisions and are the most prevalent approach to making causal claims in the social sciences. I discuss several forms of recent empirical evidence indicating that questionable research practices contribute to the comparative unreliability of quasi-experimental research and advocate for adopting the preregistration of such studies.
View Article and Find Full Text PDFA stochastic model for affect dynamics: methodological insights from heart rate variability in an illustrative case of Anorexia Nervosa.
Front Psychiatry
February 2025
Department of Psychology, University of Turin, Turin, Italy.
Background: Affect dynamics, or variations in emotional experiences over time, are linked to psychological health and well-being, with moderate emotional variations indicating good psychophysical health. Given the impact of emotional state on cardiac variability, our objective was to develop a quantitative method to measure affect dynamics for better understanding emotion temporal management in Anorexia Nervosa (AN).
Methods: The study proposed an experimental and methodological approach to evaluate physiological affect dynamics in clinical settings.
ERS Congress 2024: highlights from the Interstitial Lung Diseases Assembly.
ERJ Open Res
March 2025
Department of Respiratory Medicine, Erasmus Medical Center, University Hospital Rotterdam, Rotterdam, The Netherlands.
https://bit.ly/3WAhw19.
View Article and Find Full Text PDFManaging Opioid Tolerance: Balancing Pain Relief and Tackling Addiction.
Curr Drug Saf
March 2025
Department of Pharmaceutics, ISF College of Pharmacy, Moga, Punjab 142001, India.
This editorial discusses opioid tolerance, a growing challenge in managing pain in chronic patients. With time, overuse of opioids causes less sensitivity and responsiveness of opioid receptors and leads to higher doses of opioids for the same level of pain management. Due to this, it increases the risk of side effects, such as opioid addiction, respiratory issues, and overdose.
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