Fucoidans are branched sulfated polysaccharides primarily derived from brown seaweed, especially the Fucus genus, as well as other algae and marine invertebrates. With pseudoplastic behavior, they offer promising applications in cosmetics, pHarmaceuticals, and food industries. While traditional drug delivery materials are well-studied, fucoidans have gained attention as encapsulants, particularly in combination with chitosan and whey protein concentrate, which enhances their biocompatibility, biodegradability, and bioactivity. These combinations enable effective encapsulation of bioactive compounds, drugs, and microorganisms. Despite these advantages, research on fucoidans as encapsulants is limited, with few studies exploring the mechanisms behind their function. This review examines the potential of fucoidans in encapsulation, addressing both their benefits and the challenges in expanding their applications across pharmaceutical, nutraceutical, and related fields.
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http://dx.doi.org/10.1016/j.foodchem.2025.143570 | DOI Listing |
Heliyon
February 2025
Department of Fisheries, Qaemshahr Branch, Islamic Azad University, Qaemshahr, Iran.
This study investigates the problem of preserving the quality and shelf life of beluga sturgeon () fillets under refrigeration. The aim of the research is to evaluate the effectiveness of composite edible coatings made from chitosan and fucoidan, in combination with crucian carp () protein hydrolysate (CPH). Significant methodology includes the preparation of hydrolyzed proteins using the enzyme Alcalase for 90 min, followed by encapsulation within nanoliposomes.
View Article and Find Full Text PDFFood Chem
February 2025
Guangdong Provincial Key Laboratory of Food Quality and Safety, College of Food Science, South China Agricultural University, Guangzhou 510642, China.
Fucoidans are branched sulfated polysaccharides primarily derived from brown seaweed, especially the Fucus genus, as well as other algae and marine invertebrates. With pseudoplastic behavior, they offer promising applications in cosmetics, pHarmaceuticals, and food industries. While traditional drug delivery materials are well-studied, fucoidans have gained attention as encapsulants, particularly in combination with chitosan and whey protein concentrate, which enhances their biocompatibility, biodegradability, and bioactivity.
View Article and Find Full Text PDFInt J Biol Macromol
February 2025
School of Medical Laboratory Science and Biotechnology, College of Medical Science and Technology, Taipei Medical University, Taipei 110, Taiwan; Ph.D. Program in Medical Biotechnology, College of Medical Science and Technology, Taipei Medical University, Taipei 110, Taiwan; Department of Laboratory Medicine, Taipei Medical University Hospital, Taipei 110, Taiwan. Electronic address:
Vaccination is one of the most effective strategies for preventing infectious diseases. Recently, most research has centered on the development of protein subunit vaccines due to their safety. However, their low immunogenicity remains a challenge.
View Article and Find Full Text PDFInt J Mol Sci
February 2025
Faculty of Medicine, Division of Infectious Diseases, University of British Columbia, Vancouver, BC V6H3Z6, Canada.
Intracellular pathogens represent a challenge for therapy because the antibiotics used need to diffuse into the cytoplasm to target the pathogens. The situation is more complicated in the mycobacteria family because members of this family infect and multiply within macrophages, the cells responsible for clearing microorganisms in the body. In addition, mycobacteria members are enclosed inside pathogen-containing vesicles or phagosomes.
View Article and Find Full Text PDFInt J Biol Macromol
April 2025
School of Food Science and Technology, Jiangnan University, Wuxi 214122, PR China. Electronic address:
Rutin, a promising bioactive hydrophobic compound, suffers from poor physicochemical stability, resulting in low bioavailability. Herein, we used positively charged chitosan and negatively charged fucoidan as biopolymers coating rutin-nanoliposome (RNL) via electrostatic layer-by-layer self-assembly approach to prepare fucoidan/chitosan-coated rutin-nanoliposome (FC-RNL). The FC-RNL exhibited the encapsulation efficiency of 77.
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