Purpose: The construction sector has the highest risk of fatal and non-fatal injuries worldwide. This study examined the impact of risk mitigation strategies implemented in Qatar's construction sector between 2013 and 2021 on non-fatal injuries.
Methods: This study employed quantitative and qualitative methods. Data on implemented strategies were gathered through a systematic website search and structured interviews with Safety and Occupational Health officers. Retrospective injury data were obtained from Hamad Trauma Center medical records. Systematic website search identified key legislation and guidelines. Interview transcripts were analyzed using qualitative content analysis. Injury data were categorized into pre- and post-implementation data. Differences were assessed using means, standard deviations, percentages, effect sizes, and confidence intervals.
Results: Eight safety legislation/policies and guidelines were issued. Interview analysis identified technical, behavioral, and organizational measures as key themes in risk mitigation strategies. Comparing pre- and post-implementation data, non-fatal injury incidence (effect size (ES): 0.21, 95% CI 0.19-0.28) and severity (ES: 0.32, 95% CI 0.25-0.40) were reduced. Hospital and ICU stays were shorter post-implementation (ES: 0.2, 95% CI 0.12-0.27 and 0.014, 95% CI 0.010-0.021). Injury reductions were observed across major affected areas, except for the chest and skin. Non-fatal injuries remained more common among general laborers (ES: - 0.26, 95% CI - 0.34, 0.18) and those wearing protective devices (ES; - 0.1, CI - 0.12, - 0.07).
Conclusion: Implemented risk mitigation strategies collectively reduced non-fatal injury incidence and severity and improved outcomes in the construction sector. Future research should explore observed trends through prospective studies and job hazard analysis.
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http://dx.doi.org/10.1007/s00420-025-02126-x | DOI Listing |
Ren Fail
December 2025
Department of Nephrology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, People's Republic of China.
Background: IgA nephropathy (IgAN) presents a challenging spectrum of outcomes, often complicated by intrarenal arterial/arteriolar lesions (IALs) in affected individuals. Despite their clinical relevance, existing criteria for classifying and assessing the severity of these lesions remain undefined. This study aimed to establish semi-quantitative assessment criteria for grading IALs and to evaluate their prognostic significance in patients with IgAN.
View Article and Find Full Text PDFBMJ Open
March 2025
Faculty of Medicine, University of Indonesia, Jakarta, Indonesia.
Objectives: This systematic review examines prehospital and in-hospital delays in acute stroke care in Indonesia.
Design: Systematic review adhering to Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines.
Data Sources: We conducted a thorough search across 11 databases, ClinicalTrials.
Int Immunopharmacol
March 2025
School of Integrative Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China. Electronic address:
Atherosclerosis is a chronic inflammatory disease in which mitochondrial DNA (mtDNA) has emerged as a key contributor to its pathogenesis. We synthesized evidence from experimental and clinical studies showing that mtDNA damage, release, and mutation profoundly affect endothelial cells, macrophages, and vascular smooth muscle cells, thereby driving plaque initiation and progression. By activating immune signaling pathways-including cGAS-STING, NLRP3 inflammasome, and TLR9-mtDNA amplifies inflammation and oxidative stress, exacerbating atherosclerotic lesion development.
View Article and Find Full Text PDFEcotoxicol Environ Saf
March 2025
Department of Health Management, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Shandong Engineering Laboratory for Health Management, Shandong Medicine and Health Key Laboratory of Laboratory Medicine, Jinan, China; Department of Medical Record Management and Statistics, The First Affiliated Hospital of Shandong First Medical University &Shandong Provincial Qianfoshan Hospital, Jinan, China. Electronic address:
Background: High oxidative balance score (OBS) may mitigate inflammation levels and thereby alleviate the adverse health effects induced by toxic metals. We assessed the independent, joint effects as well as their interactions of toxic metals and OBS on mortality among individuals with non-alcoholic fatty liver diseases (NAFLD).
Methods: Participants with NAFLD from the National Health and Nutrition Examination Survey (NHANES) 1999-2018 were included.
Chemosphere
March 2025
Herbert Wertheim College of Engineering, Engineering School of Sustainable Infrastructure and the Environment (ESSIE), Department of Environmental Engineering Sciences, University of Florida, 408 A.P. Black Hall, Gainesville, FL, 32611, United States. Electronic address:
Per- and polyfluoroalkyl substances (PFAS) are persistent environmental pollutants, and their presence in aquatic environments, especially coastal waters, poses significant ecological and human health risks. This study investigates the occurrence and behavior of four PFAS compounds in the Indian River Lagoon, a biodiverse estuarine ecosystem located in Florida USA, by evaluating how ecological and hydroclimatic factors influence PFAS occurrence. A Bayesian Logistic Regression Model (BLRM) was employed to quantify the relationships between environmental stressors such as salinity, precipitation, river discharge, water temperature, and pH, and the presence of these PFAS compounds.
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