Objectives: ITP is not only a bleeding disease but also a potential thrombotic disease.
Methods: This retrospective study analyzed the factors associated with the occurrence of thrombosis events in ITP patients.
Results: The overall incidence of thrombosis was 4.66% (15/322), with the incidence of arterial events was 2.17% (7/322) and of venous thrombosis was 2.80% (9/322). Thrombosis can occur in all stages and was more common in patients with chronic ITP (66.7%). In univariate logistic analysis, age (OR = 1.037, 95%CI (1.003,1.072), = 0.032), hypertension (OR = 3.389, 95%CI (1.184,9.699), = 0.023), coronary artery disease (OR = 10.714, 95%CI (2.462,46.619), = 0.002), dyslipidemia (OR = 4.325, 95%CI (1.463,12.788), = 0.008), and treatment with TPO-RAs (OR = 5.233, 95%CI (1.448,18.918), = 0.012) were related to increased risk thrombotic events. In multivariate logistic analysis, results showed that coronary artery disease (OR = 9.486, 95% CI (1.858, 48.42), = 0.007), dyslipidemia (OR = 3.983, 95% CI (1.255, 12.641), = 0.019), as well as TPO-RAs treatment (OR = 4.591, 95% CI (1.238, 17.023), = 0.023), were independent risk factors for thrombosis in ITP patients ( < 0.05).
Conclusions: Thrombotic events can occur at all stages of ITP with a higher percentage in chronic ITP. Coronary artery disease, dyslipidemia and TPO-RAs treatment are independent risk factors related to thrombosis in ITP patients.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1080/16078454.2025.2472461 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
In Vivo Behavior of Transitional Foods as Compared to Purees: A Videofluoroscopic Analysis.
Am J Speech Lang Pathol
March 2025
Communication Disorders and Sciences, University of Oregon, Eugene.
Purpose: Medically tailored transitional foods (TFs) may be a clinically viable alternative to pureed consistency for individuals requiring texture-modified foods. However, little remains known about the performance of TFs during the swallow. The purpose of this investigation was to describe oropharyngeal swallowing physiology in patients with dysphagia during consumption of TFs as compared to pureed solids.
View Article and Find Full Text PDFEffect of SMS Ward Round Notifications on Inpatient Experience in Acute Medical Settings: Retrospective Cohort Study.
JMIR Hum Factors
March 2025
Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, 82, Gumi-ro 173 Beon-gil, Bundang-gu, Gyeonggi-do, Seongnam-si, 13620, Republic of Korea, 82 317877085.
Background: Ward rounds are an essential component of inpatient care. Patient participation in rounds is increasingly encouraged, despite the occasional complicated circumstances, especially in acute care settings.
Objective: This study aimed to evaluate the effect of real-time ward round notifications using SMS text messaging on the satisfaction of inpatients in an acute medical ward.
Type A Aortic Dissection Following Abdominal Solid Organ Transplantation: Population-Level Outcomes in the United States.
Clin Transplant
March 2025
Division of Cardiac Surgery, CardioVascular Center, Tufts Medical Center, Boston, Massachusetts, USA.
Background: This study aims to analyze the patient characteristics, clinical outcomes, and contemporary trends concerning type A aortic dissection (TAAD) in previous recipients of abdominal solid organ transplantation (ASOT) in the United States.
Methods: The National Inpatient Sample was queried to identify all patients aged ≥18 with TAAD and a history of ASOT (TAAD-ASOT) between 2002 and 2015Q3 using ICD-9 diagnosis and procedure codes. Baseline characteristics and in-hospital outcomes were compared between TAAD-ASOT patients and TAAD patients without a history of ASOT (TAAD-non-ASOT).
A New Method Using the Four-Chamber View to Identify Fetuses With Subsequently Confirmed Postnatal Aortic Coarctation.
Echocardiography
March 2025
Division of Pediatric Cardiology, Department of Pediatrics, UCLA Mattel Children's Hospital, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.
Objective: To determine the sensitivity, specificity, and false-positive rate among fetuses suspected prenatally to have coarctation of the aorta (CoA) using size and shape measurements of the fetal heart from the four-chamber view (4CV).
Methods: This was a retrospective study of 108 fetuses identified by pediatric cardiologists to be at risk for CoA. 4CV s from the last antenatal ultrasound performed by the cardiologists were analyzed.
Frequency of Culture-proven Bacterial Infection and Radiographic Pneumonia in Pediatric Heart Transplant Recipients.
Pediatr Infect Dis J
March 2025
Divisions of Pediatric Emergency Medicine and Pediatric Infectious Diseases, Baylor College of Medicine, Houston, Texas.
Background: Infection is a leading cause of death after pediatric heart transplants (PHTs). Understanding of common pathogens is needed to guide testing strategies and empiric antibiotic use.
Methods: We conducted a 3-center retrospective study of PHT recipients ≤18 years old presenting to cardiology clinics or emergency departments (EDs) from 2010 to 2018 for evaluation of suspected infections within 2 years of transplant.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!