Drug-induced gingival enlargement often occurs due to patient's lack of awareness about the side effects of prescribed medications. This case report details an unusual instance of massive drug-induced gingival overgrowth in a 50-year-old female, successfully managed through a multidisciplinary approach, including surgical intervention and prosthetic rehabilitation. The surgical treatment involved multiple extractions and the excision of excessive tissue. Both arches healed completely after surgery, and the patient underwent prosthetic rehabilitation, with no signs of recurrence. Effective management of such cases relies on patient counseling and appropriate drug substitution. Increasing awareness about the side effects of certain medications and the connection between systemic and oral health is crucial to prevent such cases of gingival enlargement.
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http://dx.doi.org/10.4103/jisp.jisp_147_23 | DOI Listing |
J Indian Soc Periodontol
January 2025
MSc Public Health Student, University of East London, London, UK.
Drug-induced gingival enlargement often occurs due to patient's lack of awareness about the side effects of prescribed medications. This case report details an unusual instance of massive drug-induced gingival overgrowth in a 50-year-old female, successfully managed through a multidisciplinary approach, including surgical intervention and prosthetic rehabilitation. The surgical treatment involved multiple extractions and the excision of excessive tissue.
View Article and Find Full Text PDFItal J Pediatr
February 2025
Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties "Giuseppe D'Alessandro", University of Palermo, Palermo, Italy.
Background: KBG syndrome (MIM #148050) is a rare genetic disease, showing an autosomal dominant pattern of inheritance. It was first described by Herrmann et al. in 1975 in three affected families, whose initial letters gave origin to the acronym.
View Article and Find Full Text PDFRom J Morphol Embryol
February 2025
Department of Histology, Department of Oral and Maxillofacial Surgery, Faculty of Dental Medicine, University of Medicine and Pharmacy of Craiova, Romania;
The oral mucosa can suffer a series of traumatic injuries from various causes (bacterial plaque, tartar, fillings, incorrectly adapted prosthesis). A risk factor generating periodontal diseases is represented by fixed orthodontic therapy, if the forces exerted on it are excessive. These forces cause more or less extensive injuries both on the surface and in depth.
View Article and Find Full Text PDFClin Adv Periodontics
February 2025
Department of Periodontology, Peking University School and Hospital of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Laboratory for Digital and Material Technology of Stomatology & NHC Research Center of Engineering and Technology for Computerized Dentistry & Beijing Key Laboratory of Digital Stomatology, Beijing, China.
Background: Systemic diseases often present initial signs through oral manifestations, making early recognition essential for accurate diagnosis and effective treatment planning. Patients with acute lymphoblastic leukemia (ALL) commonly experience gingival issues. This case report discusses the treatment and outcomes of a 12-year-old female patient who presented with gingival swelling and pain and was subsequently diagnosed with ALL.
View Article and Find Full Text PDFDiagnostics (Basel)
January 2025
Dental School, Vita-Salute San Raffaele University, IRCCS San Raffaele, 20132 Milan, Italy.
: Drug-induced gingival enlargement is a commonly documented adverse effect in patients administered with calcium antagonist medications. Nifedipine is the medicine most frequently linked to instances of gingival enlargement; nevertheless, amlodipine, likewise a calcium antagonist, can elicit this adverse effect. This case report aims to detail a case of amlodipine-induced gingival hyperplasia, emphasizing the significance of a multidisciplinary approach and outlining its therapy across various surgical phases.
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