Dermoscopy of Onychopapilloma: A Benign Mimic of Subungual Malignancy.

Cureus

Department of Dermatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA.

Published: January 2025

Onychopapilloma is a benign tumor of the nail bed and distal matrix, commonly presenting with longitudinal erythronychia and distal subungual hyperkeratosis. A 30-year-old Asian male presented with an asymptomatic, stable discoloration of the thumbnail, with longitudinal erythronychia, distal onycholysis, and V-shaped fissuring. Dermoscopy revealed splinter hemorrhages and focal distal subungual hyperkeratosis beneath the V-shaped notch. The lesion was unchanging over several years, and the patient opted for conservative management with periodic monitoring rather than biopsy. Based on clinical and dermoscopic features, onychopapilloma can often be distinguished from malignant conditions such as amelanotic melanoma and squamous cell carcinoma. Differential diagnoses include glomus tumor, trauma, Darier disease, and lichen planus. While biopsy is not needed for stable, asymptomatic cases, it is recommended if the lesion changes or becomes symptomatic.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11865681PMC
http://dx.doi.org/10.7759/cureus.78103DOI Listing

Publication Analysis

Top Keywords

onychopapilloma benign
8
longitudinal erythronychia
8
erythronychia distal
8
distal subungual
8
subungual hyperkeratosis
8
dermoscopy onychopapilloma
4
benign mimic
4
mimic subungual
4
subungual malignancy
4
malignancy onychopapilloma
4

Similar Publications

Dermoscopy of Onychopapilloma: A Benign Mimic of Subungual Malignancy.

Cureus

January 2025

Department of Dermatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA.

Onychopapilloma is a benign tumor of the nail bed and distal matrix, commonly presenting with longitudinal erythronychia and distal subungual hyperkeratosis. A 30-year-old Asian male presented with an asymptomatic, stable discoloration of the thumbnail, with longitudinal erythronychia, distal onycholysis, and V-shaped fissuring. Dermoscopy revealed splinter hemorrhages and focal distal subungual hyperkeratosis beneath the V-shaped notch.

View Article and Find Full Text PDF

Background: A wide variety of tumors can affect the nail unit, with some commonly mistaken as inflammatory or infectious diseases. Obtaining an optimal sample for histopathologic evaluation requires understanding of nail unit anatomy as well as the histopathology of the suspected nail tumor.

Summary: This review discusses clinical and histopathologic features of a subset of benign and malignant nail tumors, including subungual melanoma, nail unit squamous cell carcinoma in situ, nail unit squamous cell carcinoma, onychomatricoma, onychopapilloma, onychocytic matricoma, and onychocytic carcinoma.

View Article and Find Full Text PDF

Diagnosis and Management of Malignant Epithelial Nail Unit Tumors.

Diagnostics (Basel)

October 2024

Dermatology Department, Saint Pierre and Brugmann University Hospitals, Université Libre de Bruxelles, 1000 Brussels, Belgium.

Article Synopsis
  • Malignant tumors of the nail unit, like squamous cell carcinoma and basal cell carcinoma, can be hard to diagnose because they often look like benign issues, making early detection important.
  • * This review examines various types of malignancies affecting the nail unit, discussing their clinical features, pathology, and surgical management challenges.
  • * Proper evaluation and treatment strategies are critical for improving patient outcomes and preserving nail function during surgery.*
View Article and Find Full Text PDF

Introduction: Subungual acantholytic dyskeratotic acanthoma is a rare benign tumor of epidermal keratinocytes characterized by acantholysis and dyskeratosis. Only 7 other cases have been published in the literature.

Case Presentation: A 29-year-old male presented with painful erythronychia and onycholysis of the left thumbnail.

View Article and Find Full Text PDF

Diagnosis and management of longitudinal erythronychia: A clinical review by an expert panel.

J Am Acad Dermatol

September 2024

Department of Dermatology, Weill Cornell Medicine, New York, New York. Electronic address:

Longitudinal erythronychia (LE) is defined as a longitudinal red band of the nail(s) and is classified as localized (involvement of 1 nail) or polydactylous (involvement of more than 1 nail). The differential diagnosis is distinct for these classifications. The etiologies of localized longitudinal erythronychia are most frequently benign subungual neoplasms and less often malignancies.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!