Sinonasal inverted papilloma is an expansive, benign mass derived from the Schneiderian membrane. It may undergo malignant transformation and most commonly originates from the maxillary sinuses or the lateral walls of the nasal corridors. This case outlines the case of a sinonasal inverted papilloma, which clearly arises from the posterior ethmoid sinus, bordering the skull base. This abnormal originating point was able to be identified during endoscopic excision of the mass and involved mucosa. The ethmoid bone was not resected as it would expose the dura mater, risking CSF leak and complications. This case further supports the use of endoscopy in the investigation of sinonasal inverted papilloma rather than the gold standard approach of lateral rhinotomy. An endoscopic approach allowed for improved safety when accessing the posterior ethmoid cavity. This case also highlights the possibility of novel origins of sinonasal inverted papilloma, such as the membrane of the posterior ethmoid cavity.
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http://dx.doi.org/10.1155/crot/8389174 | DOI Listing |
Cureus
February 2025
Department of Otorhinolaryngology, The Jikei University Hospital, Tokyo, JPN.
Objectives: The postoperative recurrence rate of sinonasal inverted papilloma (IP) is high, and the residual tumor at the attachment site (the pedicle of the tumor) is considered the main cause of recurrence. Therefore, a surgical approach tailored to the tumor attachment is crucial. Localized hyperostosis is an imaging characteristic of the attachment observed on computed tomography (CT).
View Article and Find Full Text PDFCase Rep Otolaryngol
February 2025
Department of Otolaryngology, Anne Burnett Marion School of Medicine, Texas Christian University, 2800 South University Dr, Fort Worth 76109, Texas, USA.
Sinonasal inverted papilloma is an expansive, benign mass derived from the Schneiderian membrane. It may undergo malignant transformation and most commonly originates from the maxillary sinuses or the lateral walls of the nasal corridors. This case outlines the case of a sinonasal inverted papilloma, which clearly arises from the posterior ethmoid sinus, bordering the skull base.
View Article and Find Full Text PDFJ Craniomaxillofac Surg
February 2025
Department of Otorhinolaryngology Head and Neck Surgery, The Affiliated Hospital of Qingdao University, Qingdao, China. Electronic address:
Objectives: In previous study, we have found that preoperative serum squamous cell carcinoma antigen (SCCA) and cytokeratin 19 fragment antigen 21-1(CYFRA 21-1) could be used as serum tumor markers for the diagnosis of sinonasal inverted papilloma (SNIP). Thus, we detected the expression of SCCA and CYFRA 21-1 in tumor tissue and serum to further demonstrate the role of SCCA and CYFRA21-1 in SNIP and other differential diseases.
Methods: Clinical data including gender, age, and preoperative serum SCCA and CYFRA 21-1 levels were obtained respectively from 34,91,59 patients with chronic rhinosinusitis with nasal polyps (CRSwNP), SNIP, and sinonasal squamous cell carcinoma (SNSCC).
Rhinology
February 2025
Department of Otolaryngology/Head and Neck Surgery, Hospital de la Santa Creu i Sant Pau, Spain.
Sinonasal inverted papilloma (IP) often appears as a unilateral sinonasal soft-tissue mass with varying enhancement, often accompanied by bone remodelling, intralesional calcifications, focal hyperostosis, and cone-shaped bone thickening (observed in 60 to 80% of cases) (1,2). A non-contrast sinonasal CT scan may reveal a soft tissue polypoid mass that closely resembles inflammatory polyps (Figure 1 A-D). While hyperostosis is recognized as a marker of the tumor's point of origin (1), intralesional calcifications are less frequently described but may offer valuable insights.
View Article and Find Full Text PDFAnn Maxillofac Surg
September 2024
Department of Oral and Maxillofacial Surgery, Sri Siddhartha Dental College and Hospital, Tumakuru, Karnataka, India.
Rationale: Sinonasal tumours are rare occurrences accounting for 3-4% of tumours (benign/malignant/co-existing) in the head-and-neck region, making it difficult to render an absolute diagnosis and treatment, thereof keeping in mind the tumour presentation and quality of life of the patient.
Patient Concerns: The patient reported with complaints of swelling over the right side of the face associated with recent onset of pain in the same region.
Diagnosis: Upon clinical, radiographic and histopathological examination, it was diagnosed as right Sinonasal inverted papilloma (SNIP).
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