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| http://dx.doi.org/10.1016/j.hrcr.2024.10.021 | DOI Listing |
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Endocardial autonomic denervation of the left atrium to treat recurrent micturition syncope.
HeartRhythm Case Rep
February 2025
Cardiac Arrhythmia Center, Fuwai Hospital, National Center for Cardiovascular Diseases, National Key Laboratory, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Endocardial gaglionated plexi ablation in different vagally-mediated clinical settings: From cardioneuroablation to cardio-neuromodulation.
Eur Heart J Suppl
February 2025
Department of Cardiology, Policlinico Casilino, Via Casilina 1049, Rome, Italy.
Cardioneuroablation (CNA) is now recognized as a safe and effective method in patients with cardioinhibitory neurocardiogenic syncope (CNCS), especially in young patients in order to avoid or prolong, as much as possible, the timing of definitive cardiac pacing. Several investigations have shown beneficial and very satisfactory results with a standard non-extensive endocardial ablation, aimed at identifying high-amplitude fragmented signals in the right and left atria. Despite this, the current scientific debate is focused about a proposal on an ablative method, even more individualized than CNA (at least as a first approach), considering that a standardized approach, especially in the left atrium, could expose CNCS patients with a good prognosis to an excessive risk of complications.
View Article and Find Full Text PDFHypertension-induced heart failure disrupts cardiac sympathetic innervation.
Am J Physiol Heart Circ Physiol
December 2024
Department of Chemical Physiology and Biochemistry, Oregon Health & Science University, Portland, Oregon, United States.
About 26 million people worldwide live with heart failure (HF), and hypertension is the primary cause in 25% of these cases. Autonomic dysfunction and sympathetic hyperactivity accompany cardiovascular diseases, including HF. However, changes in cardiac sympathetic innervation in HF are not well understood.
View Article and Find Full Text PDFEndocardial ablation of ganglionated plexus for the treatment of carotid sinus syndrome.
J Cardiovasc Electrophysiol
January 2025
Arrythmias Unit, University Hospital of Santiago de Compostela, Santiago, Spain.
Article Synopsis
- Carotid sinus syndrome (CSS) leads to severe vagal responses and often requires pacemaker implantation, but this study explores cardioneuroablation (CNA) as a potential alternative treatment.
- The study included 13 patients who underwent various tests before and after the CNA procedure, aiming for no cardioinhibitory response post-treatment and analyzing quality of life improvements.
- Results showed that, after CNA, all but one patient had a negative response to carotid sinus massage, with 84.6% remaining free from syncope and no one needing a pacemaker, indicating CNA may effectively reduce syncopal episodes in CSS patients.
Mechanisms of Vein of Marshall-Related Tachyarrhythmias and the Impact of Ethanol Infusion.
Rev Cardiovasc Med
April 2024
Department of Cardiac Pacing and Electrophysiology, Bordeaux University Hospital (CHU), 33000 Bordeaux, France.
The Ligament of Marshall (LOM) is a remnant of the embryonic sinus venosus and the left cardinal vein, containing a combination of fat, fibrous tissue, blood vessels, muscle bundles, nerve fibers, and ganglia. Various muscular connections exist between the LOM and the left atrium (LA) and the coronary sinus (CS). The LOM is richly innervated by autonomic nerves, with ganglion cells distributed around it.
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