Introduction: 'Shocks' or external stressors to vaccination programmes can lead to decreased vaccination coverage rates. The capacity of vaccination ecosystems to effectively respond and adapt to shocks demonstrates programme resilience. This study sought to describe components that contribute to resilience in national immunisation programmes.
Methods: Mixed-methods study comprising in-depth interviews and surveys with n=30 vaccination programme experts in eight countries (Brazil, Costa Rica, Greece, Japan, Nigeria, Philippines, Spain and the USA). We elicited data on country-specific shocks, associated effects and factors that facilitated or impeded programme resilience. Interviews and open-ended survey responses were analysed qualitatively, with closed-ended survey questions analysed using descriptive statistics.
Results: Experts described immediate effects of shocks including decreased vaccine uptake and negative perceptions of vaccination from the public and media. Late emerging impacts included increased vaccine hesitancy and vaccine-preventable disease (VPD) rates. Stakeholder education, immunisation information systems (IIS) and programme financing were key factors to strengthening programme resilience. Appropriately trained frontline healthcare personnel can counter vaccine misinformation that otherwise erodes trust and contributes to hesitancy. The COVID-19 pandemic also exposed structural weaknesses in programme resilience, with experts highlighting the need for robust IIS and workforce support to mitigate burnout and strengthen resilience when a shock occurs.
Conclusions: Our findings provide preliminary insights into factors that experts believe to be associated with vaccination programme resilience. Anticipating, adapting and responding to shocks is central to strengthening systems, ensuring ecosystem resilience and protecting against current and future VPD threats.
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http://dx.doi.org/10.1136/bmjph-2023-000381 | DOI Listing |
Braz J Biol
March 2025
IPB University, Faculty of Mathematics and Natural Sciences, Department of Biochemistry, Bogor, Indonesia.
The Abelmoschus esculentus L. Moench, commonly known as okra, is increasingly cultivated in Indonesia due to its recognition as a functional food source. Current efforts in breeding new okra varieties are focused on high productivity, yet minimal information is available regarding selection criteria.
View Article and Find Full Text PDFRev Bras Enferm
March 2025
Universidade Federal Fluminense. Niterói, Rio de Janeiro, Brazil.
Objectives: to map evidence on undergraduate students' mental health globally during the COVID-19 pandemic.
Methods: a scoping review, in which PRISMA-ScR was used.
Results: twenty-six articles were included, from which data were collected on the characteristics of articles, participants involved, and results.
JAMA Netw Open
March 2025
Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill.
Importance: Frailty assessed at a single time point is associated with mortality in older women with breast cancer. Little is known about how changes in frailty following cancer treatment initiation affect mortality.
Objective: To evaluate the association between claims-based frailty trajectories following adjuvant chemotherapy initiation and 5-year mortality in older women with stage I to III breast cancer.
Adv Mater
March 2025
School of Chemical Engineering, Nanjing University of Science and Technology, Nanjing, 210094, P. R. China.
Bioelectrodes function as a critical interface for signal transduction between living organisms and electronics. Conducting polymers (CPs), particularly poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate), are among the most promising materials for bioelectrodes, due to their electrical performance, high compactness, and ease of processing, but often suffer from degradation or de-doping even in some common environments (e.g.
View Article and Find Full Text PDFNanomaterials (Basel)
February 2025
Institute of Materials and Environmental Chemistry, HUN-REN Research Centre for Natural Sciences, Magyar Tudósok Körútja 2, H-1117 Budapest, Hungary.
Sn-doped TiO-carbon composites were identified as promising multifunctional supports for Pt electrocatalysts, in which the oxide component enhances resistance against corrosion and strong metal-support interactions at the Pt-oxide boundary ensure high stability for the Pt nanoparticles. This work is devoted to the study of the influence of preliminary functionalization of the carbon on the properties of Pt/TiSnO-C catalysts. The structural, compositional and morphological differences between the samples prepared using functionalized or unmodified carbon, as well as the effect of carbon pre-modification on the electrocatalytic behavior of the synthesized Pt catalysts, were investigated using TEM, XRD, XPS, nitrogen adsorption and electrochemical measurements.
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