Purpose: The aim of the present study was to compare clinical and radiological outcomes between the all-inside single bundle (SB) and a modified double-bundle (DB) anterior cruciate ligament reconstructions (ACLR) at over 5-year follow-up.

Methods: This is an observational, retrospective comparative, two-centre study. Clinical outcomes were evaluated using Lysholm and International Knee Documentation Committee (IKDC) scores, and anterior tibial translation (ATT) was assessed using the KT-1000 arthrometer. Knee x-ray images were recorded, classified according to the KL grading and compared with radiographs of the same patient before surgery. Inclusion criteria were patients undergoing ACLR, age between 18 and 45 years and negative knee history of major traumatic events after surgery. Exclusion criteria were congenital laxity, combined multiple knee ligament injuries, patients undergoing ACL revision surgery, history of infection, lower limb coronal axial deviation >5°, patients undergoing lateral extra-articular tenodesis or anterolateral ligament reconstruction, patients with chondral damage Outerbridge grade >2, patients with meniscal tears undergoing subtotal meniscectomy or meniscal repair and patients with knee OA Kellgren-Lawrance (KL) grade >3.

Results: One hundred and fifty-two patients were included in the study. Patients were divided into two groups according to surgical technique: Group A-ACLR with all-inside technique, and Group B-ACLR with modified DB technique. There were no statistical differences between groups for age, side, gender or time since surgery.There were no statistically significant differences between groups for Lysholm scores ( = 0.43), IKDC ( = 0.88), ATT ( = 0.105) and KL grade ( = 0.93 before surgery, 0.99 at the fu). KL grade increased significantly since pre-op.

Conclusions: Our data show significant improvements in all clinical outcome measures, along with excellent KT-1000 arthrometer values and low clinical failure rates for both the SB all-inside and modified DB techniques at a mean follow-up of over 6 years. There were no significant differences in arthritic progression according to KL grade between groups.

Level Of Evidence: Level III.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11867162PMC
http://dx.doi.org/10.1002/jeo2.70100DOI Listing

Publication Analysis

Top Keywords

patients undergoing
12
modified double-bundle
8
double-bundle anterior
8
anterior cruciate
8
cruciate ligament
8
ligament reconstruction
8
kt-1000 arthrometer
8
patients
8
technique group
8
differences groups
8

Similar Publications

Cancer therapy-related cardiac dysfunction (CTRCD) is a major concern for patients undergoing cardiotoxic cancer treatments. Sodium-glucose co-transporter-2 (SGLT2) inhibitors have shown cardioprotective effects in both diabetic and non-diabetic populations. However, their impact on CTRCD risk remains uncertain.

View Article and Find Full Text PDF

Introduction: Distress is common among cancer patients, especially those undergoing surgery. However, no study has systematically analyzed distress trends in this population. The purpose of this study was to systematically review perioperative rates of distress, as well as differences across cancer types, in cancer patients undergoing surgical intervention.

View Article and Find Full Text PDF

Background: Postoperative haemorrhage following palatine tonsillectomy occurs in 5-14% of cases. Since 2021, our department has used knot suturing with 3-0 Vicryl, and from 2023, continuous suturing with the V-Loc closure device to reduce suture time. While knot suturing is reported to reduce postoperative bleeding and pain, no studies have compared outcomes between different suture methods.

View Article and Find Full Text PDF

Bruton tyrosine kinase covalent inhibition shapes the immune microenvironment in chronic lymphocytic leukemia.

Haematologica

March 2025

Experimental Hematology, Vall d'Hebron Institute of Oncology (VHIO), Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain; Department of Medicine, Universitat Autònoma de Barcelona, Bellaterra.

Continuous treatment with ibrutinib not only exerts tumor control but also enhances T cell function in patients with chronic lymphocytic leukemia (CLL). We conducted longitudinal multi-omics analyses in samples from CLL patients receiving ibrutinib upfront to identify potential adaptive mechanisms to Bruton tyrosine kinase (BTK) inhibition during the first 12 months of continuous therapy. We found that ibrutinib induced a decrease in the expression of exhaustion markers and the proportion of Tregs and Tfh cells normalized to levels observed in healthy donors.

View Article and Find Full Text PDF

Scope: The uremic toxin trimethylamine N-oxide (TMAO) accumulates in patients with chronic kidney disease (CKD) and is associated with its progression, cardiovascular disease, and other complications. The gut microbiota produces TMAO from substrates mainly found in red meat, eggs, and dairy. However, some saltwater fish also contain high levels of TMAO.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!