Zwitterionic liquids have attracted significant attention in various fields due to their low-toxicity and the ability to tune their functional properties. However, despite being liquid in thermo-dynamic definition, zwitterionic liquids are not commonly recognized as "liquids" by the general public because of their extremely high viscosity, comparable to that of peanut butter, which prevents stirring even with a strong magnetic stirrer. In this study, we developed a flowable and stirrable zwitterionic liquid, OEimOEC. Its viscosity was one-seventeenth that of traditional zwitterionic liquids. OEimOEC was able to stir and dissolve 11 wt% cellulose at 100 °C, which is a task unachievable by a typical zwitterionic liquid due to their high viscosity. Furthermore, OEimOEC exhibited low toxicity to yeast, consistent with other standard zwitterionic liquids. This study successfully achieved a significant reduction in viscosity without compromising other properties.
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http://dx.doi.org/10.1039/d4cc06448h | DOI Listing |
Langmuir
March 2025
Department of Chemistry and Materials Engineering, Kansai University, 3-3-35, Yamate-cho, Suita, Osaka 564-8680, Japan.
Associative phase separation (complex coacervation) in liquid-liquid phase separation (LLPS) involves the separation of multiple substances into concentrated and dilute phases by electrostatic interactions. Simple phase separation (simple coacervation) occurs when the hydrophilicity and hydrophobicity of a single molecule change dramatically in response to a specific stimulus. Simple coacervation arises from the lower critical solution temperature (LCST)- and upper critical solution temperature (UCST)-type phase separations in aqueous media containing temperature-responsive polymers.
View Article and Find Full Text PDFNat Commun
March 2025
Engineering Research Center of Organosilicon Compounds & Materials, Ministry of Education, College of Chemistry and Molecular Sciences, Wuhan University, Wuhan, 430072, PR China.
Here are described the dilution-driven gel-sol-gel-sol transitions in aromatic hydrotrope/zwitterionic surfactant bi-component aqueous mixtures. Long and entangled wormlike micelles (WLMs) of concentrated erucyl dimethyl amidopropyl betaine (EAPB) solutions sequentially transform into hexagonal liquid crystal phase (H), highly concentrated spherical micelles (HCSMs), and finally hexagonal close packed micellar phase (HCP) upon gradual introducing an aromatic hydrotrope, sodium salicylate (NaSal). The HCP then successively converts into HCSMs, WLMs, and spherical micelles (SMs) upon further dilution with water, corresponding to a gel-sol-gel-sol transition.
View Article and Find Full Text PDFDalton Trans
March 2025
Department of Chemistry, Birla Institute of Technology and Science Pilani, Hyderabad, India.
This study investigated the interaction of ciprofloxacin (CIP) with three different ionic liquids (ILs) featuring distinct cationic residues (pyrrolidinium, IL, . imidazolium, IL, with bis(trifluoromethylsulfonyl)imide as the counter anion) and counter anions bis(trifluoromethylsulfonyl)imide, IL, . hexafluorophosphate, IL, with imidazolium as the cationic residue) in an aqueous environment.
View Article and Find Full Text PDFChem Commun (Camb)
February 2025
Faculty of Biological Science and Technology, Graduate School of Natural Science and Technology, Kanazawa University, Kakuma-machi, Kanazawa 920-1192, Japan.
Zwitterionic liquids have attracted significant attention in various fields due to their low-toxicity and the ability to tune their functional properties. However, despite being liquid in thermo-dynamic definition, zwitterionic liquids are not commonly recognized as "liquids" by the general public because of their extremely high viscosity, comparable to that of peanut butter, which prevents stirring even with a strong magnetic stirrer. In this study, we developed a flowable and stirrable zwitterionic liquid, OEimOEC.
View Article and Find Full Text PDFACS Nano
March 2025
Research Center for Translational Medicine, Medical Innovation Center and State Key Laboratory of Cardiology, Shanghai East Hospital; The Institute for Biomedical Engineering & Nano Science, Tongji University School of Medicine, Shanghai 200120, China.
Cardiovascular disease (CAD) is a major global public health issue, with mortality rates being significantly impacted by cold temperatures. Stable and reliable electrocardiogram (ECG) monitoring in cold environments is crucial for early detection and treatment of CAD. However, existing skin sensor struggle to balance freeze resistance, breathability, flexibility, conductivity and adhesion at cold temperatures.
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