Objectives: This study evaluates the efficacy of a new temporomandibular joint (TMJ) capsule suspension technique for stabilizing the TMJ after free fibular flap reconstruction of the mandibular condyle.
Patients And Methods: Patients undergoing the TMJ capsule suspension technique during free fibular flap reconstruction after mandibulectomy with condylectomy (study group; n=9) were compared with a control group (n=9). Mandibular movement trajectory and surface electromyographic signals of bilateral masseters were recorded. The neocondyle-disc relationship was examined with magnetic resonance imaging (MRI) at 6 months after surgery.
Results: Maximal mouth opening and bilateral marginal movement distances were comparable between the two groups (>0.05). The asymmetry index of the condyle path length was significantly higher in controls (=0.02). Bilateral mouth opening trajectories were symmetric in 7 patients and deviated to the affected side in 2 patients in the study group; they deviated to the affected side in all controls. The mean electromyographic values of the masseter on the affected side in resting, maximum bite, and chewing states were comparable between the two groups (=0.13, =0.65, and =0.82, respectively). On MRI at 6 months, the thicknesses of the anterior, medial, and posterior bands and TMJ disc length were similar on the affected and normal sides in the study group (=0.57, =0.13, =0.48, and =0.87, respectively).
Conclusion: The proposed TMJ capsule suspension technique could improve postoperative TMJ structure and function after fibular free flap reconstruction following mandibulectomy with condylectomy.
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http://dx.doi.org/10.5125/jkaoms.2025.51.1.46 | DOI Listing |
J Korean Assoc Oral Maxillofac Surg
February 2025
Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing, China.
Objectives: This study evaluates the efficacy of a new temporomandibular joint (TMJ) capsule suspension technique for stabilizing the TMJ after free fibular flap reconstruction of the mandibular condyle.
Patients And Methods: Patients undergoing the TMJ capsule suspension technique during free fibular flap reconstruction after mandibulectomy with condylectomy (study group; n=9) were compared with a control group (n=9). Mandibular movement trajectory and surface electromyographic signals of bilateral masseters were recorded.
World J Microbiol Biotechnol
February 2025
Department of Internal Medicine II, Infectious Diseases, Goethe University Frankfurt, University Hospital Frankfurt, Frankfurt am Main, Germany.
Fecal microbiota transplantation (FMT) effectively treats recurrent Clostridioides difficile infection (rCDI), typically administered as a fresh or frozen stool suspension through colonoscopy, nasojejunal tube, or oral capsules. Lyophilized fecal microbiota (LFM) are an alternative to frozen FM products. We aimed to assess whether lyophilization affects bacterial viability and metabolite levels and to develop LFM capsules for clinical use in Germany.
View Article and Find Full Text PDFKorean J Radiol
March 2025
Department of Medical Imaging, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Objective: To assess the effect of transarterial embolization (TAE) for adhesive capsulitis (AC) by evaluating clinical outcomes and changes in inflammation using magnetic resonance imaging (MRI).
Materials And Methods: Patients who had undergone TAE between August 2020 and August 2023 for AC refractory to conservative treatments without any invasive procedures for more than 3 months, and had undergone baseline and 3-month post-AC follow-up contrast-enhanced MRI evaluations, were included. A suspension mixture of 500 mg imipenem/cilastatin in 10 mL of iodinated contrast agent was used for TAE.
Carbohydr Polym
April 2025
State Key Laboratory of Ecological Pest Control for Fujian and Taiwan Crops & Key Laboratory of Biopesticide and Chemical Biology of Ministry of Education, College of Life Science and College of Plant Protection, Fujian Agriculture and Forestry University, Fuzhou 350002, Fujian, China. Electronic address:
Bacillus thuringiensis (Bt) is affected by ultraviolet radiation and bacterial sedimentation in pest control applications, leading to low pesticide utilization and a short duration of control. To improve Bt stability in these applications and prolong the duration of biological control, Bt LLP29 was first encapsulated using double emulsion technology, resulting in the formation of W/O/W double emulsion microcapsules with sodium lignosulfonate and chitosan as wall materials. The morphological structure and functionality of microcapsules were then systematically investigated.
View Article and Find Full Text PDFExpert Rev Neurother
February 2025
Neurological Clinic, Marche Polytechnic University, Ancona, Italy.
Introduction: Zonisamide (ZNS), is an antiseizure medication (ASM) approved by the US FDA and the European Medicines Agency (EMA) for focal-onset seizures. An oral suspension formulation has recently been introduced to improve administration for specific patient populations, particularly those with swallowing difficulties.
Areas Covered: This article explores the new ZNS oral suspension, evaluating its pharmacokinetic benefits, impact on patient care, and adherence.
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