In recent years, DC microgrids supplying constant power loads (CPLs) have attracted significant attention due to their impact on overall system stability, which is attributed to their electrical characteristics that exhibit negative incremental impedance. This paper examines a secondary control strategy aimed at ensuring accurate power sharing and voltage restoration within an islanded DC microgrid supplying a constant power load. The droop control function is typically used in the primary control layer to facilitate power sharing among distributed generators (DGs). However, differing load profiles may cause the DC bus voltage to deviate from its nominal value. To restore the DC bus voltage to its nominal value while maintaining accurate power sharing, a primary and secondary control scheme is proposed. This scheme employs an integrated control strategy combining sliding mode control for the primary control level and H-infinity control for secondary control. The approach is based on a two-time-scale stability analysis, i.e., the settling time of the primary control must be faster than that of the secondary control. Additionally, compared to most existing methods, the proposed approach requires no global information and depends exclusively on DC bus voltage feedback, eliminating the need for passive loads in parallel with the CPL. A test system of an islanded DC microgrid feeding a CPL is created using Matlab and PSIM software to assess the proposed method. An experimental prototype comprising two DGs and a tightly voltage-controlled boost converter emulating a CPL is developed to demonstrate the proposed approach and confirm the theoretical results.
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http://dx.doi.org/10.1038/s41598-025-89318-0 | DOI Listing |
Cancer Med
March 2025
Institute of Microcirculation, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Background: Tumor metastasis is one of the main causes of death in cancer patients; however, the mechanism controlling metastasis is unclear. The posttranscriptional regulation of metastasis-related genes mediated by AT-rich interactive domain-containing protein 4A (Arid4a), an RNA-binding protein (RBP), has not been elucidated.
Methods: Bioinformatic analysis, qRT-PCR, immunohistochemistry, and immunoblotting were employed to determine the expression of Arid4a in breast tumor tissues and its association with the survival of cancer patients.
A 73-year-old woman presented with a pancreas divisum was admitted for acute pancreatitis. Abdominal CT was performed due to a torpid evolution with fever and oral intolerance, demonstrating necrosis and ductal disruption in the pancreatic neck. An ERCP was attempted, however, the minor papilla (MP) could not be identified because of the presence of edematous duodenal folds.
View Article and Find Full Text PDFNutr Hosp
March 2025
Facultad de Medicina. Universidad de Castilla-La Mancha.
Introduction: currently there are changes in lifestyle that have been modifying the nutritional culture, moving away from the Mediterranean diet (DMed) and acquiring a more sedentary lifestyle, a fact that has contributed to a significant increase in risk factors. (CVRF) such as obesity and type 2 diabetes mellitus (DM2), and consequently to a global increase in metabolic syndrome (MS) and cardiovascular diseases (CVD), which in the 21st century reinforces being the first cause of morbidity and mortality To reduce this pandemic, a multidisciplinary approach is required focused on the application of primary and secondary prevention strategies for modifiable CVRFs, focused on nutritional promotion and education through the promotion of a healthier lifestyle and diet from childhood, as the one that encompasses the MedD. This dietary pattern, together with physical exercise, has been shown to contribute to the primary and secondary prevention of DM2 and coexisting CVRF.
View Article and Find Full Text PDFPers Med Psychiatry
April 2024
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA.
Background: We previously identified a cognitive biotype of depression characterized by dysfunction of the brain's cognitive control circuit, comprising the dorsolateral prefrontal cortex (dLPFC) and dorsal anterior cingulate cortex (dACC), derived from functional magnetic resonance imaging (fMRI). We evaluate these circuit metrics as personalized predictors of antidepressant remission.
Methods: We undertook a secondary analysis of data from the international Study to Predict Optimized Treatment in Depression (iSPOT-D) for 159 patients who completed fMRI during a GoNoGo task, 8 weeks treatment with one of three study antidepressants and who were assessed for remission status (Hamilton Depression Rating Scale score of ≤ 7).
Front Neurol
February 2025
Department of Human Movement Sciences, Faculty of Behavioural and Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam Movement Sciences, Amsterdam, Netherlands.
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