Purpose: To determine if short-term patient reported outcomes (PROs) following meniscal allograft transplantation (MAT) correlate with mid- to long-term PROs at a minimum of 5-year follow-up.
Methods: A retrospective review was performed of MATs performed between 2001 and 2019 that had preoperative, 2-year, and minimum 5-year postoperative PROs. Patient-reported outcomes of interest assessed included International Knee Documentation Committee (IKDC) Score, all subscales of the Knee Injury and Osteoarthritis Outcome Score (KOOS), and Lysholm score. Short-term, mid-term, and long-term PROs were defined as 2 years, 5-10 years, and ≥10 years respectively. Mid-term and long-term outcomes were analyzed separately. Patients were evaluated for the achievement of previously reported thresholds for minimally clinically important difference (MCID), patient acceptable symptomatic state (PASS) and substantial clinical benefit (SCB). Logistic regression was used to compare improvements in PROs with respect to reoperation. Linear regression was used to analyze the correlation between short-term and mid- to long-term improvements in PROs.
Results: 54 patients (48.1% male, 51.9% female) with a mean age of 30.0 ± 10.5 years and BMI of 26.2 ± 4.2 were included. Mean follow-up for the entire cohort was 10.4 ± 4.4 years. MCID achievement ranged from 70.0% to 95%, PASS from 55.6% to 78.6%, and SCB from 38.5% to 69.2%. We found significant positive correlations between short-term and mid-term as well as short-term and long-term improvements in all outcomes, with the exception of Lysholm scores in the ≥ 10 years group. 18 patients (33.3%) had any subsequent reoperation on the same knee, 5 of which (9.2%) included conversion to arthroplasty.
Conclusion: Two-year improvements in PROs following MAT are predictive of sustained success at mid-term and long-term follow-up, with significant correlations observed between 2-year outcomes and those at 5 - 10 and ≥10 years.
Level Of Evidence: IV; Case Series.
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