Purpose: To evaluate postpartum hemorrhage (PPH) and Interventional Radiology (IR) service landscapes in Kenya using geospatial analytic mapping for outreach planning.
Materials And Methods: Geographic information system (GIS) analysis of Kenya was performed using open-source data sets. Data at the regional and county levels from 2014-2018 were collected to evaluate demographics and variables related to PPH and healthcare access. Population risk indices were created based on these data. Detailed multi-layered GIS mapping was performed to produce visual data representations of the findings for outreach planning.
Results: From 2014 to 2018, the incidence of maternal hemorrhage in Kenya increased by 38%. Six hospitals in Kenya offer the IR services required to treat PPH, all located in Nairobi. Relative to other counties, maternal mortality ratios (MMRs) in Nairobi were near the median, falling within standard deviations of -0.5 to 0.5. MMRs were highest in the southeastern and northwestern regions of the country, with standard deviation increases of 1.5-2.3 and 0.5-1.5 respectively. Risk index and population maps identified high-impact hospitals for IR outreach.
Conclusion: GIS analysis demonstrated disproportionate rates of maternal morbidity and mortality due to PPH in areas without IR capabilities. It proved to be a valuable tool to understand population health and can be leveraged to strategically target global IR services.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/j.jvir.2025.02.019 | DOI Listing |
Sci Adv
March 2025
School of Science and Engineering, Chinese University of Hong Kong, Shenzhen, China.
Intrabronchial delivery of therapeutic agents is critical to the treatment of respiratory diseases. Targeted delivery is demanded because of the off-target accumulation of drugs in normal lung tissues caused by inhalation and the limited motion dexterity of clinical bronchoscopes in tortuous bronchial trees. Herein, we developed microrobotic swarms consisting of magnetic hydrogel microparticles to achieve intrabronchial targeted delivery.
View Article and Find Full Text PDFRadiol Med
March 2025
Department of Minimally Invasive Interventional Radiology, Sun Yat-sen University Cancer Center, Sun Yat-sen University, Dongfeng East Road 651, Guangzhou, 510260, Guangdong Province, China.
Purpose: Hepatic arterial infusion chemotherapy (HAIC) combined with lenvatinib (Len) and immune checkpoint inhibitor (ICI) in treating advanced hepatocellular carcinoma (HCC) still needs further confirmation. We aimed to evaluate the efficacy of HAIC combined with Len and ICI (HAIC + Len + ICI) versus Len alone in advanced HCC.
Methods: A total of 290 patients in Len group and 349 patients in HAIC + Len + ICI group were analysed.
Aging Dis
March 2025
Department of Radiology, Peking University Third Hospital, Beijing, China.
Neurochemical imbalance is a contributing factor to neurological symptoms in multiple sclerosis (MS). The matured myelin sheath is crucial for substance transportation within the extracellular space (ECS) and for maintaining local homeostasis. Therefore, we hypothesize that disturbed ECS transportation following demyelinating lesions might lead to neurochemical imbalance in MS.
View Article and Find Full Text PDFInt J Surg
March 2025
Department of Digestive and Emergency Surgery, "S.Maria" Hospital, Terni, Italy.
Background: The management of high-surgical risk patients with moderate to severe acute cholecystitis is challenging in clinical practice. Early laparoscopic cholecystectomy is considered the gold standard for patients who do not respond to conservative treatment. However, for those unfit for surgery due to high-surgical risk, alternative treatment options such as percutaneous cholecystostomy (PC) are available.
View Article and Find Full Text PDFFront Oncol
February 2025
Hong Kong Integrated Oncology Centre, Hong Kong, Hong Kong SAR, China.
Background: Despite the boom in the development of cancer management in the last decade, most patients with metastatic prostate cancer (PCa) eventually progress to metastatic castration-resistant PCa (mCRPC) and often require multiple lines of treatment. The treatment landscape of mCRPC has evolved rapidly in recent years, introducing various types of systemic therapies, including taxane-based chemotherapy, androgen receptor pathway inhibitors, bone-targeted radionuclides (e.g.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!